Lidocaine HCl
Lidocaine HCl structure
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Common Name | Lidocaine HCl | ||
|---|---|---|---|---|
| CAS Number | 6108-05-0 | Molecular Weight | 288.814 | |
| Density | N/A | Boiling Point | 350.8ºC at 760 mmHg | |
| Molecular Formula | C14H25ClN2O2 | Melting Point | 68.5ºC | |
| MSDS | Chinese USA | Flash Point | 166ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Development and in vitro evaluation of a buccal drug delivery system based on preactivated thiolated pectin.
Drug Dev. Ind. Pharm. 40(11) , 1530-7, (2014) The aim of this study was to evaluate the potential of preactivated thiolated pectin (Pec-Cys-MNA) for buccal drug delivery. Therefore, a gel formulation containing this novel polymer and the model drug lidocaine was prepared and investigated in vitro in term... |
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Evaluation of regional limb perfusion with chloramphenicol using the saphenous or cephalic vein in standing horses.
J. Vet. Pharmacol. Ther. 38(1) , 35-40, (2015) Regional limb perfusion (RLP) significantly decreases morbidity and mortality associated with distal limb injuries in horses. There is an urgent need for finding additional effective antimicrobial drugs for use in RLP. In this study, we tested the pharmacokin... |
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Intravenous lidocaine decreases tumor necrosis factor alpha expression both locally and systemically in pigs undergoing lung resection surgery.
Anesth. Analg. 119(4) , 815-28, (2014) Lung resection surgery is associated with an inflammatory reaction. The use of 1-lung ventilation (OLV) seems to increase the likelihood of this reaction. Different prophylactic and therapeutic measures have been investigated to prevent lung injury secondary ... |
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Pre-emptive Penile Ring Block With Sucrose Analgesia Reduces Pain Response to Neonatal Circumcision
Urology 83(4) , 893-8, (2014) Objective To compare retrospective use of oral sucrose (SUC) vs oral sucrose plus lidocaine ring block (SUC + RB) in the management of pain during neonatal circumcision. |
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Inhibition of murine cardiomyocyte respiration by amine local anesthetics.
Eur. J. Drug Metab. Pharmacokinet. 39(4) , 293-9, (2014) The hydrophobic amino acyl amide-linked local anesthetics (e.g., lidocaine and bupivacaine) impose potent cardiac toxicity and direct mitochondrial dysfunction. To investigate these adverse events, an in vitro system was employed to measure their effects on O... |
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Small-volume 7.5% NaCl adenosine, lidocaine, and Mg2+ has multiple benefits during hypotensive and blood resuscitation in the pig following severe blood loss: rat to pig translation.
Crit. Care Med. 42(5) , e329-44, (2014) Currently, there is no effective small-volume fluid for traumatic hemorrhagic shock. Our objective was to translate small-volume 7.5% NaCl adenosine, lidocaine, and Mg hypotensive fluid resuscitation from the rat to the pig.Pigs (35-40 kg) were anesthetized a... |
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Lidocaine concentration in mandibular bone after subperiosteal infiltration anesthesia decreases with elevation of periosteal flap and irrigation with saline.
Anesth. Prog. 61(2) , 53-62, (2014) It has been reported that the action of infiltration anesthesia on the jawbone is attenuated significantly by elevation of the periosteal flap with saline irrigation in clinical studies; however, the reason is unclear. Therefore, the lidocaine concentration i... |
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Genipin-crosslinked catechol-chitosan mucoadhesive hydrogels for buccal drug delivery.
Biomaterials 37 , 395-404, (2015) Drug administration via buccal mucosa is an attractive drug delivery strategy due to good patient compliance, prolonged localized drug effect, and avoidance of gastrointestinal drug metabolism and first-pass elimination. Buccal drug delivery systems need to m... |
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Methemoglobinemia induced by lidocaine-prilocaine cream.
Isr. Med. Assoc. J. 16(4) , 250-4, (2014) With growing awareness of the importance of pain control in all procedures, the use of lidocaine-prilocaine cream (EMLA) for all ages is increasing. Lidocaine-prilocaine cream has been implicated as a cause of methemoglobinemia. Diagnostic clues may be oxygen... |
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Trends in pharmacy compounding for women's health in North Carolina: focus on vulvodynia.
South. Med. J. 107(7) , 433-6, (2014) To identify trends in compounding pharmacies with a focus on women's health and, more specifically, the types and combinations of medications used in the treatment of vulvodynia.This survey study was conducted with 653 nonchain pharmacies that compound medica... |