2-BUTANONE OXIME
2-BUTANONE OXIME structure
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Common Name | 2-BUTANONE OXIME | ||
|---|---|---|---|---|
| CAS Number | 96-29-7 | Molecular Weight | 87.120 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 152.5±0.0 °C at 760 mmHg | |
| Molecular Formula | C4H9NO | Melting Point | -30 °C | |
| MSDS | Chinese USA | Flash Point | 60.0±0.0 °C | |
| Symbol |
GHS05, GHS07, GHS08 |
Signal Word | Danger | |
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Slow oxidation of acetoxime and methylethyl ketoxime to the corresponding nitronates and hydroxy nitronates by liver microsomes from rats, mice, and humans.
Toxicol. Sci. 47(2) , 144-50, (1999) Acetoxime and methylethyl ketoxime (MEKO) are tumorigenic in rodents, inducing liver tumors in male animals. The mechanisms of tumorigenicity for these compounds are not well defined. Oxidation of the oximes to nitronates of secondary-nitroalkanes, which are ... |
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Single-pot template transformations of cyanopyridines on a Pd(II) centre: syntheses of ketoimine and 2,4-dipyridyl-1,3,5-triazapentadiene palladium(II) complexes and their catalytic activity for microwave-assisted Suzuki-Miyaura and Heck reactions.
Dalton Trans. (16) , 3074-84, (2009) [2 + 3] cycloaddition of the pyrrolin N-oxide (-)O[upper bond 1 start](+)N[double bond, length as m-dash]CHCH(2)CH(2)C[upper bond 1 end]Me(2) with 2-cyanopyridine NC(5)H(4)(2-CN) in the presence of PdCl(2) at room temperature in acetone gives the ketoimine pa... |
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Oxidative effects in human erythrocytes caused by some oximes and hydroxylamine.
Arch. Toxicol. 72(5) , 270-6, (1998) Both oximes and hydroxylamine (HYAM) are compounds with known oxidative capacity. We tested in vitro whether acetaldoxime (AAO), cyclohexanone oxime (CHO), methyl ethyl ketoxime (MEKO) or HYAM affect haemoglobin oxidation (into HbFe3+), formation of thiobarbi... |
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Reproductive toxicity evaluation of methylethyl ketoxime by gavage in CD rats.
Fundam. Appl. Toxicol. 31(2) , 149-61, (1996) Methylethyl ketoxime (CAS No. 96-29-7; MEKO; 2-butanone oxime), an antioxidant agent used in paints, resins, and adhesives, was tested for reproductive toxicity in a two-generation study with CD (Sprague-Dawley) rats. Thirty-eight-week-old rats/sex/group (F0)... |
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A chronic inhalation toxicity/oncogenicity study of methylethylketoxime in rats and mice.
Inhal. Toxicol. 13(12) , 1093-116, (2001) To evaluate the oncogenic potential of methylethylketoxime (MEKO), CD-1 mice (50/sex/group) and F-344 rats (50/sex/group) were coexposed 6 h/day, 5 days/wk for 18 mo (mice) or 26 mo (rats) via whole-body inhalation exposures to target vapor concentrations of ... |
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An evaluation of changes and recovery in the olfactory epithelium in mice after inhalation exposure to methylethylketoxime.
Inhal. Toxicol. 14(12) , 1249-60, (2002) Methylethylketoxime, also known as MEKO or 2-butanone oxime (CAS No. 96-29-7), is a clear, colorless to light yellow liquid at room temperature. It is an industrial antioxidant used as an antiskinning agent in alkyd paint, an industrial blocking agent for ure... |
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Oxime silanes: structure/toxicity relationships.
Drug Chem. Toxicol. 31(1) , 97-114, (2008) Acute and repeated oral and dermal rat toxicology studies of standard designs were conducted on four methyl ethyl ketoxime (MEKO) silanes and four methyl isobutyl ketoxime (MIBKO) silanes. Each compound contained either MEKO or MIBKO groups (but not both) and... |
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Disposition of methyl ethyl ketoxime in the rat after oral, intravenous and dermal administration.
Xenobiotica 28(10) , 1005-15, (1998) 1. The disposition of 14C-methyl ethyl ketoxime (MEKO) was determined in the male F344 rat following oral, intravenous (i.v.) and dermal administration. 2. Oral doses of 2.7, 27 and 270 mg/kg were primarily excreted as CO2 (71-49%) in decreasing percentage as... |
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Developmental toxicity studies of methyl ethyl ketoxime (MEKO) in rats and rabbits.
Drug Chem. Toxicol. 26(3) , 147-68, (2003) The developmental toxicity of methyl ethyl ketoxime (MEKO), an industrial antioxidant used primarily as an antiskinning agent in alkyd paint, was investigated in rats and rabbits. Following preliminary dose range finding studies, groups of 25 pregnant rats or... |
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Cobalt-Assisted Condensation of 2-Butanone Oxime and Acetone: Synthesis and X-ray Structure of the Novel Acetaldiimine Complex [CoI2 {((CH3CH2)(CH3) C= NO) 2C (CH3) 2}]. Hierso J-C , et al.
Eur. J. Inorg. Chem. 2000(12) , 2459-62, (2000)
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