Citric acid monohydrate

Citric acid monohydrate Structure
Citric acid monohydrate structure
Common Name Citric acid monohydrate
CAS Number 5949-29-1 Molecular Weight 210.139
Density 1.54 Boiling Point 56 °C760 mm Hg(lit.)
Molecular Formula C6H10O8 Melting Point 135-152 ºC
MSDS Chinese USA Flash Point 173.9 ºC
Symbol GHS07
GHS07
Signal Word Warning

Dietary vitamin D3 deficiency alters intestinal mucosal defense and increases susceptibility to Citrobacter rodentium-induced colitis.

Am. J. Physiol. Gastrointest. Liver Physiol. 309 , G730-42, (2015)

Vitamin D deficiency affects more that 1 billion people worldwide. Although thought to increase risk of bacterial infections, the importance of vitamin D on host defense against intestinal bacterial pathogens is currently unclear since injection of the active...

Magnetic graphene as modified quick, easy, cheap, effective, rugged and safe adsorbent for the determination of organochlorine pesticide residues in tobacco.

J. Chromatogr. A. 1406 , 1-9, (2015)

In this study, magnetic graphene was used as modified quick, easy, cheap, effective, rugged and safe (QuEChERS) adsorbent for the determination of organochlorine pesticide (OCPs) residues in tobacco. To achieve the optimum conditions of modified QuEChERS proc...

Development of an enzymatic assay system of D-lactate using D-lactate dehydrogenase and a UV-LED fluorescent spectrometer.

J. Pharm. Biomed. Anal. 116 , 150-5, (2015)

In this study, we aimed to develop a new enzymatic assay system of d-lactate with good precision, accuracy, and sensitivity for the determination of D-lactate concentrations in rat serum. D-Lactate dehydrogenase (D-LDH) was utilized to catalyze D-lactate and ...

Ultrasensitive and rapid screening of mercury(II) ions by dual labeling colorimetric method in aqueous samples and applications in mercury-poisoned animal tissues.

Anal. Chim. Acta 868 , 45-52, (2015)

Rapid and ultrasensitive detection of trace heavy metal mercury(II) ions (Hg(2+)) are of significant importance due to the induced serious risks for environment and human health. This presented article reports the gold nanoparticle-based dual labeling colorim...

An analytical quality by design (aQbD) approach for a L-asparaginase activity method.

J. Pharm. Biomed. Anal. 117 , 232-9, (2015)

L-asparaginase is an effective anti-tumor agent for acute lymphoblastic leukemia. This work presents the development of an activity determination of L-ASNase preparations for pharmaceutical quality control purposes, in accordance with analytical Quality by De...

Effects of solution conditions on virus retention by the Viresolve® NFP filter.

Biotechnol. Prog. 31 , 1280-6, (2015)

Virus filtration can provide a robust method for removal of adventitious parvoviruses in the production of biotherapeutics. Although virus filtration is typically thought to function by a purely size-based removal mechanism, there is limited data in the liter...

Nanonization of curcumin by antisolvent precipitation: process development, characterization, freeze drying and stability performance.

Int. J. Pharm. 477(1-2) , 564-77, (2014)

The present work aims to investigate applicability of antisolvent precipitation method for preparation of nanosized curcumin and to control their characteristics by determining the influence of process and solvents on solid-state properties of curcumin nanopa...

Combined treatment with GH and IGF-I: additive effect on cortical bone mass but not on linear bone growth in female rats.

Endocrinology 155(12) , 4798-807, (2014)

The growth-promoting effect of combined therapy with GH and IGF-I in normal rats is not known. We therefore investigated the efficacy of treatment with recombinant human (rh)GH and/or rhIGF-I on longitudinal bone growth and bone mass in intact, prepubertal, f...

Loss of Gab1 adaptor protein in hepatocytes aggravates experimental liver fibrosis in mice.

Am. J. Physiol. Gastrointest. Liver Physiol. 308(7) , G613-24, (2015)

Grb2-associated binder 1 (Gab1) adaptor protein amplifies signals downstream of a broad range of growth factors/receptor tyrosine kinases. Although these signals are implicated in liver fibrogenesis, the role of Gab1 remains unclear. To elucidate the role of ...

Development of tailored and self-mineralizing citric acid-crosslinked hydrogels for in situ bone regeneration.

Biomaterials 68 , 42-53, (2015)

Bone tissue engineering demands alternatives overcoming the limitations of traditional approaches in the context of a constantly aging global population. In the present study, elastin-like recombinamers hydrogels were produced by means of carbodiimide-catalyz...