Quinolin-5-amine

Quinolin-5-amine Structure
Quinolin-5-amine structure
Common Name Quinolin-5-amine
CAS Number 611-34-7 Molecular Weight 144.17
Density 1.2±0.1 g/cm3 Boiling Point 310.0±0.0 °C at 760 mmHg
Molecular Formula C9H8N2 Melting Point 106-109 °C(lit.)
MSDS Chinese USA Flash Point 171.5±8.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Metabolic and radiolytic reduction of 4-alkylamino-5-nitroquinoline bioreductive drugs. Relationship to hypoxia-selective cytotoxicity.

Biochem. Pharmacol. 48(8) , 1593-604, (1994)

The 4-alkylamino-5-nitroquinolines (5NQs) are a new series of bioreductive drugs that exhibit varying degrees of selective toxicity (up to 60-fold) under hypoxic conditions in cell culture. This study tested the hypothesis that differences in hypoxia-selectiv...

Quantum chemical and spectroscopic investigations of 5-aminoquinoline.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 74(5) , 1215-23, (2009)

The Fourier transform infrared (FTIR) and FT-Raman spectra of 5-aminoquinoline (5AQ) have been recorded in the range 4000-400 and 3500-100 cm(-1), respectively. The complete vibrational assignment and analysis of the fundamental modes of the compounds were ca...

Photochemistry of 5-aminoquinoline in protic and aprotic solvents

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 79(3) , 412-7, (2011)

Graphical abstract Photophysical/photochemical properties of 5-aminoquinoline (5AQ) have been investigated. In aprotic solvents, the spectra depend on the polarity. However, in protic solvents both the fluorescence intensity as well decay times show decrease ...

Aminoquinolines as fluorescent labels for hydrophilic interaction liquid chromatography of oligosaccharides.

Biol. Chem. 393(8) , 757-65, (2012)

In this study, we investigated the potential of four different aminoquinoline (AQ) compounds as fluorescent labels for glycan analysis using hydrophilic interaction liquid chromatography (HILIC) and fluorescence detection (FLD). We confirmed the optimal excit...

Metabolism of 5-aminoquinoline with liver cytosol enzyme.

Indian J. Biochem. Biophys. 30(4) , 229-33, (1993)

In vitro oxidation and acetylation of 5-aminoquinoline by rabbit liver enzyme preparation has been investigated. Incubation of 5-aminoquinoline with cytosol fraction of the enzyme preparation in the presence of acetyl coenzyme-A gave rise to three different p...