2-Ethylcaproic acid

2-Ethylcaproic acid Structure
2-Ethylcaproic acid structure
Common Name 2-Ethylcaproic acid
CAS Number 149-57-5 Molecular Weight 144.211
Density 0.9±0.1 g/cm3 Boiling Point 228.0±0.0 °C at 760 mmHg
Molecular Formula C8H16O2 Melting Point -59 °C
MSDS Chinese USA Flash Point 116.6±6.9 °C
Symbol GHS08
GHS08
Signal Word Warning

Carbonic anhydrase inhibitors. Inhibition of the β-class enzymes from the fungal pathogens Candida albicans and Cryptococcus neoformans with branched aliphatic/aromatic carboxylates and their derivatives.

Bioorg. Med. Chem. Lett. 21 , 2521-6, (2011)

The inhibition of the β-carbonic anhydrases (CAs, EC 4.2.1.1) from the pathogenic fungi Cryptococcus neoformans (Can2) and Candida albicans (Nce103) with a series of 25 branched aliphatic and aromatic carboxylates has been investigated. Human isoforms hCA I a...

Structural variation governs substrate specificity for organic anion transporter (OAT) homologs. Potential remote sensing by OAT family members.

J. Biol. Chem. 282 , 23841-53, (2007)

Organic anion transporters (OATs, SLC22) interact with a remarkably diverse array of endogenous and exogenous organic anions. However, little is known about the structural features that determine their substrate selectivity. We examined the substrate binding ...

Enabling unassisted solar water splitting by iron oxide and silicon.

Nat. Commun. 6 , 7447, (2015)

Photoelectrochemical (PEC) water splitting promises a solution to the problem of large-scale solar energy storage. However, its development has been impeded by the poor performance of photoanodes, particularly in their capability for photovoltage generation. ...

A high throughput screening system for predicting chemically-induced reproductive organ deformities.

Reprod. Toxicol. 55 , 95-103, (2015)

There is a great need for alternative testing methods for reproductive toxicants that are practical, fast, cost-effective and easy to interpret. Previously we followed a pragmatic approach using readily available tests, which was successful in predicting repr...

Protein-Resistant Biodegradable Amphiphilic Graft Copolymer Vesicles as Protein Carriers.

Macromol. Biosci. 15 , 1304-13, (2015)

The protein adsorption and self-assembly behavior of biocompatible graft copolymer, poly(lactide-co-diazidomethyl trimethylene carbonate)-g-poly(ethylene glycol) [P(LA-co-DAC)-g-PEG], were systematically studied. The graft copolymers showed enhanced resistanc...

Simultaneous analysis of the di(2-ethylhexyl)phthalate metabolites 2-ethylhexanoic acid, 2-ethyl-3-hydroxyhexanoic acid and 2-ethyl-3-oxohexanoic acid in urine by gas chromatography-mass spectrometry.

J. Chromatogr. B. Biomed. Sci. Appl. 758(2) , 213-9, (2001)

A gas chromatographic-mass spectrometric method was developed for the quantitative analysis of the three Di(2-ethylhexyl)phthalate (DEHP) metabolites, 2-ethylhexanoic acid, 2-ethyl-3-hydroxyhexanoic acid and 2-ethyl-3-oxohexanoic acid in urine. After oximatio...

Biological monitoring of exposure to di(2-ethylhexyl) phthalate in six French factories: a field study.

Int. Arch. Occup. Environ. Health 84(5) , 523-31, (2011)

The aim of this study was to assess, by biological monitoring, workers' exposure to di(2-ethylhexyl) phthalate (DEHP) in the flexible-PVC industry in France to provide additional occupational exposure data, which are particularly scarce.Over 5 days of pre-and...

Occurrence of 2-ethylhexanoic acid in foods packed in glass jars.

Food Addit. Contam. 21(8) , 811-4, (2004)

After simultaneous distillation-extraction (SDE) of commercial baby foods (n = 20) and fruit juices (n = 15) (among them 15 and eight products labelled 'organic', respectively) from 11 different suppliers, analyses performed by coupled capillary gas chromatog...

Effects of di-(2-ethylhexyl)-phthalate and its metabolites on the lipid profiling in rat HRP-1 trophoblast cells.

Arch. Toxicol. 80(5) , 293-8, (2006)

The highly directional maternal-to-fetal transfer of essential fatty acids (EFAs) across the placenta plays a critical role in guiding proper fetal development. Exposure to xenobiotics that may alter the fetal supply of EFAs/lipids could lead to fetal toxicit...

A review of the environmental fate and aquatic effects of a series of C4 and C8 oxo-process chemicals.

Chemosphere 45(3) , 339-46, (2001)

Environmental fate and aquatic effects data were examined for a series of C4 (butyl acetate, 1-butanol, isobutyl alcohol) and C8 (2-ethylhexanol and 2-ethylhexanoic acid) oxo-process chemicals. Manufacturing of these chemicals requires enclosed equipment, so ...