phenobarbital sodium

phenobarbital sodium Structure
phenobarbital sodium structure
Common Name phenobarbital sodium
CAS Number 57-30-7 Molecular Weight 254.21700
Density N/A Boiling Point N/A
Molecular Formula C12H11N2NaO3 Melting Point 175°C
MSDS USA Flash Point N/A
Symbol GHS06 GHS08
GHS06, GHS08
Signal Word Danger

Comparative study of the effects of antituberculosis drugs and antiretroviral drugs on cytochrome P450 3A4 and P-glycoprotein.

Antimicrob. Agents Chemother. 58(6) , 3168-76, (2014)

Predicting drug-drug interactions (DDIs) related to cytochrome P450 (CYP), such as CYP3A4 and one of the major drug transporters, P-glycoprotein (P-gp), is crucial in the development of future chemotherapeutic regimens to treat tuberculosis (TB) and TB/AIDS c...

Pentobarbital withdrawal and treatment in an infant in the pediatric cardiac intensive care unit.

J. Clin. Anesth. 25(1) , 62-5, (2013)

Withdrawal syndromes following administration of sedative and analgesic infusions represent a significant morbidity that is described increasingly in the pediatric critical care literature. However, there are few descriptions of pentobarbital withdrawal sympt...

Danshen (Radix Salviae Miltiorrhizae) reverses renal injury induced by myocardial infarction.

J. Tradit. Chin. Med. 35 , 306-11, (2015)

To evaluate the protection of danshen (Radix Salviae Miltiorrhizae) (SM) injection in myocardial infarction (MI) induced renal damage.Forty male C57 mice were divided into control group, MI group and SM group. In MI group, the left coronary artery was occlude...

Antiepileptic drugs as prophylaxis for post-craniotomy seizures.

Cochrane Database Syst. Rev. 2 , CD007286, (2013)

The incidence of seizures following supratentorial craniotomy for non-traumatic pathology has been estimated to be 15% to 20%; however, the risk of experiencing a seizure may vary from 3% to 92% over a five-year period. Postoperative seizures can precipitate ...

Partial epilepsy and developmental delay in infant with ring chromosome 14.

Genet. Couns. 24(1) , 81-3, (2013)

Ring chromosome 14 (r14) is clinically characterized by early-onset epilepsy, mental retardation, delayed speech, microcephaly, extremely mild facial dysmorphisms and ophthalmologic abnormalities. We report a case presenting with partial seizures and delayed ...

Risk factors for hyperammonemia in pediatric patients with epilepsy.

Epilepsia 54(6) , 983-9, (2013)

To identify risk factors for hyperammonemia in pediatric patients with epilepsy.A total of 2,944 pediatric patients (ages 0-15 years) were classified into the following three groups: a group without drug treatment (n = 445, group I), a group receiving antiepi...

[Case report; drug-induced hypersensitivity syndrome following meningoencephalitis associated with human herpes virus-6].

Nippon. Naika Gakkai Zasshi. 102(10) , 2682-4, (2013)

Phenobarbitone versus phenytoin monotherapy for partial onset seizures and generalised onset tonic-clonic seizures.

Cochrane Database Syst. Rev. 1 , CD002217, (2013)

This is an updated version of the original Cochrane review published in The Cochrane Library 2001, Issue 4.Worldwide, particularly in the developing world, phenytoin and phenobarbitone are commonly used antiepileptic drugs, primarily because they are inexpens...

First HPLC-UV method for rapid and simultaneous quantification of phenobarbital, primidone, phenytoin, carbamazepine, carbamazepine-10,11-epoxide, 10,11-trans-dihydroxy-10,11-dihydrocarbamazepine, lamotrigine, oxcarbazepine and licarbazepine in human plasma.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 925 , 1-9, (2013)

A sensitive and fast high-performance liquid chromatographic method coupled with ultraviolet detection is herein reported for the simultaneous determination of human plasma concentration of six antiepileptic drugs frequently used in clinical practice [phenoba...

Concurrent celecoxib with 5-fluorouracil/epirubicin/cyclophosphamide followed by docetaxel for stages II - III invasive breast cancer: the OOTR-N001 study.

Expert Opin. Investig. Drugs 22(3) , 299-307, (2013)

This prospective study aimed at investigating the efficacy and safety of the concurrent use of celecoxib (CXB) with 5-fluorouracil, epirubicin and cyclophosphamide (FEC), followed by docetaxel (T) in the neoadjuvant setting.A total of 64 invasive breast cance...