4-Fluoro-2-nitroaniline

4-Fluoro-2-nitroaniline Structure
4-Fluoro-2-nitroaniline structure
Common Name 4-Fluoro-2-nitroaniline
CAS Number 364-78-3 Molecular Weight 156.115
Density 1.4±0.1 g/cm3 Boiling Point 295.1±20.0 °C at 760 mmHg
Molecular Formula C6H5FN2O2 Melting Point 90-94 °C(lit.)
MSDS Chinese USA Flash Point 89.4±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

Benzimidazolone activators of chloride secretion: potential therapeutics for cystic fibrosis and chronic obstructive pulmonary disease.

J. Pharmacol. Exp. Ther. 296 , 600-611, (2001)

The diseases of cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) are characterized by mucus-congested airways. Agents that stimulate the secretion of Cl- are anticipated to facilitate mucociliary clearance and thus be of benefit in the tr...

Clozapine derived 2,3-dihydro-1H-1,4- and 1,5-benzodiazepines with D4 receptor selectivity: synthesis and biological testing.

Bioorg. Med. Chem. 12(10) , 2625-37, (2004)

Novel 4-arylpiperazin-1-yl-substituted 2,3-dihydro-1H-1,4- and 1H-1,5-benzodiazepines and their aza-analogues were synthesized as debenzoclozapine derivatives for evaluation as potential D4-ligands. While Ki values of some of the title compounds came within t...

Complexes of copper (II), nickel (II) and cobalt (II) with 2-fluoro, 5-nitroaniline and 4-fluoro, 2-nitroaniline. DeVoto G, et al.

Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 38(7) , 725-728, (1982)