4,5-Difluoro-2-nitroaniline

4,5-Difluoro-2-nitroaniline Structure
4,5-Difluoro-2-nitroaniline structure
Common Name 4,5-Difluoro-2-nitroaniline
CAS Number 78056-39-0 Molecular Weight 174.105
Density 1.6±0.1 g/cm3 Boiling Point 308.1±37.0 °C at 760 mmHg
Molecular Formula C6H4F2N2O2 Melting Point 107-108 °C(lit.)
MSDS Chinese USA Flash Point 140.1±26.5 °C
Symbol GHS07
GHS07
Signal Word Warning

Novel substituted quinoxaline 1,4-dioxides with in vitro antimycobacterial and anticandida activity.

Eur. J. Med. Chem. 37(5) , 355-66, (2002)

Thirty-six 6(7)-substituted-3-methyl- or 3-halogenomethyl-2-phenylthio-phenylsulphonyl-chloro-quinoxaline 1,4-dioxides belonging to series 3-6 were synthesised and submitted to a preliminary in vitro evaluation for antimycobacterial, anticandida and antibacte...

Design, synthesis, and antiviral evaluation of 2-chloro-5,6-dihalo-1-beta-D-ribofuranosylbenzimidazoles as potential agents for human cytomegalovirus infections.

J. Med. Chem. 40(5) , 811-8, (1997)

2-Chloro-5,6-difluorobenzimidazole (8) was prepared from 4,5-difluoro-2-nitroaniline (5) via successive reduction, cyclization, and diazotization reactions. 2-Chloro-5,6-dibromobenzimidazole (10) was obtained by a direct bromination of 2-chlorobenzimidazole (...

Synthesis of fluorinated derivatives of benzo [k] fluoranthene and indeno [1, 2, 3-cd] pyrene and 8, 9-dihydro-8, 9-epoxybenzo [k] fluoranthene. Rice JE, et al.

J. Org. Chem. 53(8) , 1775-79, (1988)