L-Carnitine hydrochloride

L-Carnitine hydrochloride Structure
L-Carnitine hydrochloride structure
Common Name L-Carnitine hydrochloride
CAS Number 6645-46-1 Molecular Weight 197.660
Density N/A Boiling Point N/A
Molecular Formula C7H16ClNO3 Melting Point 142 °C
MSDS USA Flash Point N/A

Amelioration of palmitate-induced metabolic dysfunction in L6 muscle cells expressing low levels of receptor-interacting protein 140.

Can. J. Physiol. Pharmacol. 93 , 913-22, (2015)

We have shown that reduced expression of receptor-interacting protein 140 (RIP140) alters the regulation of fatty-acid (FA) oxidation in muscle. To determine whether a high level of FA availability alters the effects of RIP140 on metabolic regulation, L6 myot...

To Break or to Brake Neuronal Network Accelerated by Ammonium Ions?

PLoS ONE 10 , e0134145, (2015)

The aim of present study was to investigate the effects of ammonium ions on in vitro neuronal network activity and to search alternative methods of acute ammonia neurotoxicity prevention.Rat hippocampal neuronal and astrocytes co-cultures in vitro, fluorescen...

Regulation of cardiac gene expression by KLF15, a repressor of myocardin activity.

J. Biol. Chem. 285 , 27449-27456, (2010)

Pathological forms of left ventricular hypertrophy (LVH) often progress to heart failure. Specific transcription factors have been identified that activate the gene program to induce pathological forms of LVH. It is likely that apart from activating transcrip...

Newborn screening for MCAD deficiency: experience of the first three years in British Columbia, Canada.

Can. J. Public Health 99 , 276-80, (2008)

Medium Chain Acyl-CoA Dehydrogenase (MCAD) Deficiency is an autosomal recessive disorder of fatty acid oxidation, with potential fatal outcome. MCAD deficiency is diagnosed by acylcarnitine analysis on newborn screening blood spot cards by tandem mass spectro...

Accurate measurement of free carnitine in dried blood spots by isotope-dilution electrospray tandem mass spectrometry without butylation.

Clin. Chim. Acta 335 , 137-45, (2003)

To test the feasibility of free carnitine (FC) determination in dried blood spot specimens (DBS) by stable isotope-dilution electrospray-ionisation tandem mass spectrometry (MS/MS).The MS/MS method established for newborn screening, measuring acylcarnitines b...

Effect of pO2 on antitumor drug cytotoxicity on MDR and non-MDR variants selected from the LoVo metastatic colon carcinoma cell line.

Anticancer Res. 28 , 55-68, (2008)

Two chemosensitive cell lines, LoVo-fusoid (LoVo-f) and LoVo-small cells (LoVo-sc) were derived from the original LoVo cell line. These two variants and the multidrug-resistant (MDR) cell line LoVo-Dox were screened for various properties. In non-permeabilize...