Perphenazine

Perphenazine Structure
Perphenazine structure
Common Name Perphenazine
CAS Number 58-39-9 Molecular Weight 403.969
Density 1.3±0.1 g/cm3 Boiling Point 580.4±50.0 °C at 760 mmHg
Molecular Formula C21H26ClN3OS Melting Point 35339ºC
MSDS USA Flash Point 304.8±30.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Simultaneous determination of β-agonists and psychiatric drugs in feeds by LC-MS-MS.

J. Chromatogr. Sci. 52(7) , 604-8, (2014)

A method was developed for the simultaneous determination of nine β-agonists (cimaterol, ractopamine, terbutaline, zilpaterol, salbutamol, clenbuterol, mabuterol, bambuterol and brombuterol) and six psychiatric drugs (diazepam, nitrazepam, oxazepam, chlorprom...

Salt effects in electromembrane extraction.

J. Chromatogr. A. 1347 , 1-7, (2014)

Electromembrane extraction (EME) was performed on samples containing substantial amounts of NaCl to investigate how the presence of salts affected the recovery, repeatability, and membrane current in the extraction system. A group of 17 non-polar basic drugs ...

Simple and sensitive screening and quantitative determination of 88 psychoactive drugs and their metabolites in blood through LC–MS/MS: Application on postmortem samples

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 970 , 1-7, (2014)

• The introduction has been modified. • More references have been added to the text. • Limitations of the method have been discussed more in detail.

The Impact of Strontium Ranelate on Metaphyseal Bone Healing in Ovariectomized Rats.

Calcif. Tissue Int. 97 , 391-401, (2015)

The following questions were addressed: whether therapy with strontium ranelate (SR) should be continued or interrupted if the fractures occur during SR treatment and whether SR could be applied directly after fracture to improve bone healing. Sprague-Dawley ...

Hydrophilic interaction chromatography versus reversed phase liquid chromatography coupled to mass spectrometry: effect of electrospray ionization source geometry on sensitivity.

J. Chromatogr. A. 1356 , 211-20, (2014)

In this study, the influence of electrospray ionization (ESI) source design on the overall sensitivity achieved in hydrophilic interaction chromatography (HILIC) and reversed phase liquid chromatography (RPLC), was investigated. State-of-the-art triple quadru...

Noninferiority of perphenazine vs. three second-generation antipsychotics in chronic schizophrenia.

J. Nerv. Ment. Dis. 202(1) , 18-24, (2014)

Noninferiority analysis is a statistical method of growing importance in comparative effectiveness research that has rarely been used in psychopharmacology. This method is used here to evaluate whether first-generation antipsychotics are clinically not inferi...

Schizophrenia research: where are we?

J. Nerv. Ment. Dis. 202(1) , 4-5, (2014)

Identification of thioridazine, an antipsychotic drug, as an antiglioblastoma and anticancer stem cell agent using public gene expression data.

Cell Death Dis. 6 , e1753, (2015)

Glioblastoma (GBM) is a common and malignant tumor with a poor prognosis. Glioblastoma stem cells (GSCs) have been reported to be involved in tumorigenesis, tumor maintenance and therapeutic resistance. Thus, to discover novel candidate therapeutic drugs for ...

Disposition of the neuroleptics perphenazine, zuclopenthixol, and haloperidol cosegregates with polymorphic debrisoquine hydroxylation.

Psychopharmacol. Ser. 10 , 230-7, (1993)

Perphenazine serum levels in patients on standard doses.

Psychopharmacol. Ser. 7 , 280-3, (1989)