Lomefloxacin hydrochloride
Lomefloxacin hydrochloride structure
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Common Name | Lomefloxacin hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 98079-52-8 | Molecular Weight | 387.809 | |
| Density | N/A | Boiling Point | 542.7ºC at 760 mmHg | |
| Molecular Formula | C17H20ClF2N3O3 | Melting Point | 290-3000C | |
| MSDS | Chinese USA | Flash Point | 282ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Occurrence and distribution of antibiotics in urban soil in Beijing and Shanghai, China.
Environ. Sci. Pollut. Res. Int. 22 , 11360-71, (2015) The recycling of reclaimed wastewater for irrigation and road cleaning is an important strategy to minimize water scarcity in megacities. However, little is known regarding the potential accumulation of antibiotics contained in reclaimed wastewater in urban s... |
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Spectroscopic study of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed in ozonated wastewater.
Water Res. 46(16) , 5235-46, (2012) This study addressed the formation and properties of degradation products of ciprofloxacin, norfloxacin and lomefloxacin formed during ozonation of secondary wastewater effluent containing these fluoroquinolone antibiotics. The generation of the degradation p... |
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Real-time visualization of photochemically induced fluorescence of 8-halogenated quinolones: lomefloxacin, clinafloxacin and Bay3118 in live human HaCaT keratinocytes.
Photochem. Photobiol. 86(4) , 792-7, (2010) Halogenoquinolones are potent and widely used antimicrobials blocking microbial DNA synthesis. However, they induce adverse photoresponses through the absorption of UV light, including phototoxicity and photocarcinogenicity. The phototoxic responses may be th... |
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Interaction study of moxifloxacin and lomefloxacin with co-administered drugs.
Pak. J. Pharm. Sci. 24(3) , 339-43, (2011) Moxifloxacin and lomefloxacin are fluoroquinolone antibiotics used in treating urinary and respiratory tract infections. Fluoroquinolones are known to have interactions with drugs that are active in gastro intestinal tract. Being moxifloxacin and lomefloxacin... |
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Interaction between holo transferrin and HSA-PPIX complex in the presence of lomefloxacin: an evaluation of PPIX aggregation in protein-protein interactions.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 97 , 1089-100, (2012) Human serum albumin (HSA) and holo transferrin (TF) are two serum carrier proteins that are able to interact with each other, thereby altering their binding behavior toward their ligands. During the course of this study, the interaction between HSA-PPIX and T... |
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Comparison of binding interactions of lomefloxacin to serum albumin and serum transferrin by resonance light scattering and fluorescence quenching methods.
J. Biomol. Struct. Dyn. 28(4) , 483-502, (2011) The interaction between lomefloxacin (LMF) and two drug carrier proteins, human serum albumin (HSA) and serum transferrin (TF), were studied and compared by fluorescence quenching, resonance light scattering (RLS), and circular dichroism (CD) spectroscopic al... |
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Molecular spectroscopy and chemometrics: an analytical study of synergistic effects of drugs--interaction between fluoroquinolones and DNA.
Analyst 134(9) , 1840-7, (2009) Three commonly used fluoroquinolone antibiotics (norfloxacin (NFX), ofloxacin (OFX) and lomefloxacin (LMFX)) were used as examples of molecules which can interact with a biomacromolecule, such as DNA, separately or in a mixture. Such interactions were investi... |
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Ligational behaviour of lomefloxacin drug towards Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Th(IV) and UO(2)(VI) ions: synthesis, structural characterization and biological activity studies.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 82(1) , 8-19, (2011) Nine new mononuclear Cr(III), Mn(II), Fe(III), Co(II), Ni(II), Cu(II), Zn(II), Th(IV) and UO(2)(VI) complexes of lomefloxacin drug were synthesized. The structures of these complexes were elucidated by elemental analyses, IR, XRD, UV-vis, (1)H NMR as well as ... |
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Simultaneous determination of norfloxacin and lomefloxacin in milk by first derivative synchronous fluorescence spectrometry using Al (III) as an enhancer.
Anal. Chim. Acta 707(1-2) , 128-34, (2011) A novel method for the simultaneous determination of norfloxacin (NFLX) and lomefloxacin (LFLX) in milk samples was developed by using first derivative synchronous fluorimetry. The synchronous fluorescence (Δλ=160 nm) spectra and first derivative synchronous ... |
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Photoreactivity of fluoroquinolones: nature of aryl cations generated in water.
Org. Lett. 14(15) , 3940-3, (2012) The nature of stabilized aryl cations generated from photodehalogenations of fluoroquinolones in aqueous media has been studied by comparing the photophysical and photochemical behavior of lomefloxacin (LFX) and its N(4')-acetylated form (ALFX). Photoproduct ... |