BetaMethasone 21-Valerate

BetaMethasone 21-Valerate Structure
BetaMethasone 21-Valerate structure
Common Name BetaMethasone 21-Valerate
CAS Number 2240-28-0 Molecular Weight 476.57700
Density 1.24g/cm3 Boiling Point 607.5ºC at 760 mmHg
Molecular Formula C27H37FO6 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Danger

Metabolism of topical drugs within the skin, in particular glucocorticoids.

Curr. Probl. Dermatol. 21 , 61-6, (1993)

Acid- and salt-triggered multifunctional poly(propylene imine) dendrimer as a prospective drug delivery system.

Biomacromolecules 5(2) , 524-9, (2004)

A novel dendrimeric compound is designed with the objective of simultaneously addressing issues commonly encountered in drug delivery, i.e., stability in biological milieu as well as targeting. For this purpose, a multifunctional dendrimeric system derived fr...

Postural skin colour changes during the corticosteroid blanching assay.

Skin Pharmacol. Appl. Skin Physiol. 12(4) , 199-210, (1999)

To assess the effect of the position of a limb (dependency) on the cutaneous vasoconstrictor (blanching) assay (VCA) using topical corticosteroid preparations.Two studies were performed on the forearms of healthy volunteers using tristimulus reflectance color...

Simultaneous diffusion and metabolism of betamethasone 17-valerate in the living skin equivalent.

J. Pharm. Sci. 84(12) , 1478-81, (1995)

Simultaneous diffusion and metabolism of betamethasone 17-valerate was studied using betamethasone 17-valerate, betamethasone 21-valerate, and betamethasone as permeants. These corticosteroids were suspended in silicone adhesive and applied to an artificial l...

Metabolism and degradation of betamethasone 17-valerate in homogenized living skin equivalent.

Dermatology 188(1) , 13-7, (1994)

The metabolism of betamethasone 17-valerate was estimated using an artificial living skin equivalent (LSE). Betamethasone 17-valerate, betamethasone 21-valerate and betamethasone were measured by a normal-phase high-performance liquid chromatographic (HPLC) m...

A randomized controlled trial to evaluate short-term treatment with eosin vs. topical steroids in psoriasis.

Clin. Exp. Dermatol. 34(3) , 304-8, (2009)

The therapeutic effects of some histological staining agents on psoriasis have been reported in the past. One of these agents is eosin, which is still currently used in routine treatment, although it has never been formally tested in a randomized controlled t...

Lichen amyloidosis in a dark skinned patient.

G. Ital. Dermatol. Venereol. 145(1) , 135-8, (2010)

Lichen amyloidosis is a primary localized cutaneous amyloidosis without systemic involvement, characterized by a persistent pruritic eruption of multiple discrete hyperkeratotic papules. The etiology is unknown, but chronic irritation of the skin has been pro...