Ingenol 3-mebutate

Ingenol 3-mebutate Structure
Ingenol 3-mebutate structure
Common Name Ingenol 3-mebutate
CAS Number 75567-37-2 Molecular Weight 430.534
Density 1.3±0.1 g/cm3 Boiling Point 576.9±50.0 °C at 760 mmHg
Molecular Formula C25H34O6 Melting Point N/A
MSDS Chinese USA Flash Point 191.4±23.6 °C

RasGRPs are targets of the anti-cancer agent ingenol-3-angelate.

PLoS ONE 8 , e72331, (2013)

Ingenol-3-angelate (I3A) is a non-tumor promoting phorbol ester-like compound identified in the sap of Euphoria peplus. Similar to tumor promoting phorbol esters, I3A is a diacylglycerol (DAG) analogue that binds with high affinity to the C1 domains of PKCs, ...