2-Nitro-3-pyridinol

2-Nitro-3-pyridinol Structure
2-Nitro-3-pyridinol structure
Common Name 2-Nitro-3-pyridinol
CAS Number 15128-82-2 Molecular Weight 140.097
Density 1.5±0.1 g/cm3 Boiling Point 383.2±22.0 °C at 760 mmHg
Molecular Formula C5H4N2O3 Melting Point 69-71 °C(lit.)
MSDS Chinese USA Flash Point 185.6±22.3 °C
Symbol GHS07
GHS07
Signal Word Warning

Novel sulfonate derivatives: potent antimitotic agents.

Bioorg. Med. Chem. Lett. 11(13) , 1671-3, (2001)

The synthesis and biological evaluation of novel sulfonate analogues of E-7010 are reported. Several of the compounds are potent inhibitors of cell proliferation and tubulin polymerization. Importantly, these compounds are also active against P-glycoprotein p...