thiodiacetic acid
thiodiacetic acid structure
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Common Name | thiodiacetic acid | ||
|---|---|---|---|---|
| CAS Number | 123-93-3 | Molecular Weight | 150.153 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 377.0±27.0 °C at 760 mmHg | |
| Molecular Formula | C4H6O4S | Melting Point | 128-131 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 181.8±23.7 °C | |
| Symbol |
GHS05 |
Signal Word | Danger | |
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New insights into the biodegradation of thiodiglycol, the hydrolysis product of Yperite (sulfur mustard gas).
J. Appl. Microbiol. 106 , 1111-1121, (2009) To isolate thiodiglycol (TDG)-degrading bacteria, the mustard gas hydrolysis product, and to characterize the metabolites formed and the enzymes involved in the degradation.Two strains, identified as Achromobacter xylosoxydans G5 and Paracoccus denitrificans ... |
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[Thiodiglycol metabolism in Alcaligenes xylosoxydans subsp. denitrificans].
Mikrobiologiia 71(5) , 604-10, (2002) The investigation of the degradation of thiodiglycol (the major product of mustard gas hydrolysis) by Alcaligenes xylosoxydans subsp. denitrificans strain TD2 showed that thiodiglycol is metabolized through the oxidation of its primary alcohol groups and the ... |
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Dialkyl 3,3'-thiodipropionate and dialkyl 2,2'-thiodiacetate antioxidants by lipase-catalyzed esterification and transesterification.
J. Agric. Food Chem. 54(8) , 2957-63, (2006) Medium- and long-chain dialkyl 3,3'-thiodipropionate antioxidants such as dioctyl 3,3'-thiodipropionate, didodecyl 3,3'-thiodipropionate, dihexadecyl 3,3'-thiodipropionate, and di-(cis-9-octadecenyl) 3,3'-thiodipropionate were prepared in high yield by lipase... |
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Biocatalytic transformation of [(2-Hydroxyethyl)thio]acetic acid and thiodiglycolic acid from thiodiglycol by Alcaligenes xylosoxydans ssp. xylosoxydans (SH91).
Biotechnol. Prog. 16(3) , 363-7, (2000) A Gram-negative bacterium, Alcaligenes xylosoxydans ssp. xylosoxydans (SH91), consumed thiodiglycol (TDG), the nontoxic hydrolysis product of sulfur mustard, as a primary carbon source and transformed TDG to commercially relevant chemical precursors, [(2-hydr... |
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Surface-activated chemical ionization-electrospray mass spectrometry in the analysis of urinary thiodiglycolic acid.
Rapid Commun. Mass Spectrom. 27(3) , 476-80, (2013) Thiodiglycolic acid (TDGA) is a urinary metabolite of the oxazaphosphorine class of chemotherapeutics, in particular of ifosfamide. Ifosfamide metabolism generates chloroacetaldehyde (CAA), a toxic compound associated with neurotoxicity, nephrotoxicity, uroto... |
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Transformation of thiodiglycol by resting cells of Alcaligenes xylosoxydans PGH10.
Biotechnol. Prog. 18(2) , 252-6, (2002) A new strain of Alcaligenes xylosoxydans able to aerobically cometabolize thiodiglycol, the primary hydrolysis product of sulfur mustard, was isolated and tested in a laboratory scale stirred tank reactor. The strain, named PGH10, cannot use TDG as sole carbo... |
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Supplemented creatine induces changes in human metabolism of thiocompounds and one- and two-carbon units.
Physiol. Res. 59(3) , 431-42, (2010) The administration of creatine (5 g/day for one month) to 11 young active sportsmen affected their urinary excretion of creatine, creatinine, and thiodiglycolic acid (TDGA) as well as blood levels of homocysteine, vitamin B12 and folates. The probands were di... |
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Diagnostic significance of urinary thiodiglycolic acid as a possible tool for studying the role of vitamins B12 and folates in the metabolism of thiolic substances.
Physiol. Res. 56(1) , 113-22, (2007) We have found that the determination of thiodiglycolic acid (TDGA) in urine may help to characterize metabolic imbalance of substances participating in methionine synthesis, which leads to hyperhomocystinuria. From the metabolic scheme, based on a proper comb... |
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Investigations on metabolism and carcinogenicity of 1,1,2-trichloroethane.
J. Cancer Res. Clin. Oncol. 114(2) , 158-62, (1988) Two groups of male and female Sprague-Dawley rats (50 animals/group per sex) were treated with either 15.37 or 46.77 mumole of 1,1,2-TCE in DMSO/rat for 2 years. The animals were treated once a week by s.c. injection of test compound in the skin of neck. Two ... |
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Thiodiacetic acid--a metabolite of Ethylene oxide.
Z. Naturforsch., C, J. Biosci. 52(1-2) , 70-6, (1997) Urine samples of premature babies contain high amounts of thiodiacetic acid (TDA). Since these pre-term infants are exposed to an increased oxygen atmosphere in the incubator, we supposed that these high levels of thiodiacetic acid might be produced from ethy... |