trazodone hydrochloride
trazodone hydrochloride structure
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Common Name | trazodone hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 25332-39-2 | Molecular Weight | 408.325 | |
| Density | N/A | Boiling Point | 528.5ºC at 760 mmHg | |
| Molecular Formula | C19H23Cl2N5O | Melting Point | 223ºC | |
| MSDS | USA | Flash Point | 273.4ºC | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
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Case records of the Massachusetts General Hospital. Case 4-2015. A 49-year-old man with obtundation followed by agitation and acidosis.
N. Engl. J. Med. 372(5) , 465-73, (2015) A 49-year-old man was admitted to this hospital after being found unresponsive outdoors; he was next to a half-filled bottle of cloudy liquid with pill fragments. An electrocardiogram showed a QTc interval of 501 msec. A diagnostic test was performed. Present... |
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Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.
Brain 138 , 3221-37, (2015) Polyglutamine diseases are a class of dominantly inherited neurodegenerative disorders for which there is no effective treatment. Here we provide evidence that activation of serotonergic signalling is beneficial in animal models of Machado-Joseph disease. We ... |
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Spectroscopic and calorimetric studies on trazodone hydrochloride-phosphatidylcholine liposome interactions in the presence and absence of cholesterol.
Biochim. Biophys. Acta 1838(10) , 2369-79, (2014) The interaction of antidepressant drug trazodone hydrochloride (TRZ) with dipalmitoyl phosphatidylcholine (DPPC) multilamellar liposomes (MLVs) in the presence and absence of cholesterol (CHO) was investigated as a function of temperature by using Electron Pa... |
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5-HT receptor subtypes as key targets in mediating pigment dispersion within melanophores of teleost, Oreochromis mossambicus.
Comp. Biochem. Physiol. B Biochem. Mol. Biol. 164(2) , 117-23, (2013) The presence of distinct class of 5-HT receptors in the melanophores of tilapia (Oreochromis mossambicus) is reported. The cellular responses to 5-HT (5-hydroxytryptamine), 5-HT(1), and 5-HT(2), agonists on isolated scale melanophores were observed with regar... |
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Simultaneous Quantitation of 78 Drugs and Metabolites in Urine with a Dilute-And-Shoot LC-MS-MS Assay.
J. Anal. Toxicol. 39 , 335-46, (2015) A novel LC-MS-MS assay that simultaneously detects and quantitates 78 drugs and metabolites was developed and validated for chronic pain management. Urine specimen was diluted and mixed with internal standards (ISs) before injected into LC-MS-MS. Seventy-two ... |
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Antidepressants for patients with tinnitus.
Cochrane Database Syst. Rev. 9 , CD003853, (2012) This is an update of a Cochrane review first published in The Cochrane Library in Issue 4, 2006 and previously updated in 2009.Tinnitus is described as the perception of sound or noise in the absence of real acoustic stimulation. It has been compared with chr... |
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Effects of sedative antidepressants on prefrontal cortex activity during verbal fluency task in healthy subjects: a near-infrared spectroscopy study.
Psychopharmacology 226(1) , 75-81, (2013) Japanese researchers have recently conducted studies using near-infrared spectroscopy (NIRS) to help diagnose psychiatric disorders based on changes in brain activity. However, the influence of psychotropic drugs on NIRS measurements has not been clarified.To... |
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Commentary.
Clin. Chem. 58(12) , 1635, (2012)
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Commentary.
Clin. Chem. 58(12) , 1634-5, (2012)
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Prescription compliance or illicit designer drug abuse?
Clin. Chem. 58(12) , 1631-4, (2012)
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