Calcifediol
Calcifediol structure
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Common Name | Calcifediol | ||
|---|---|---|---|---|
| CAS Number | 63283-36-3 | Molecular Weight | 418.65 | |
| Density | N/A | Boiling Point | 529.2ºC at 760 mmHg | |
| Molecular Formula | C27H46O3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 221.4ºC | |
| Symbol |
GHS02, GHS07 |
Signal Word | Danger | |
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Silver dopants for targeted and untargeted direct analysis of unsaturated lipids via infrared matrix-assisted laser desorption electrospray ionization (IR-MALDESI).
Rapid Commun. Mass Spectrom. 28(22) , 2461-70, (2014) Unsaturated lipids play a crucial role in cellular processes as signaling factors, membrane building blocks or energy storage molecules. However, adequate mass spectrometry imaging of this diverse group of molecules remains challenging. In this study we imple... |
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Analysis of oxysterols and vitamin D metabolites in mouse brain and cell line samples by ultra-high-performance liquid chromatography-atmospheric pressure photoionization-mass spectrometry.
J. Chromatogr. A. 1364 , 214-22, (2014) We have developed an ultra-high-performance liquid chromatography-atmospheric pressure photoionization-tandem mass spectrometric (UHPLC-APPI-MS/MS) method for the simultaneous quantitative analyses of several oxysterols and vitamin D metabolites in mouse brai... |
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Improved analysis of vitamin D metabolites in plasma using liquid chromatography tandem mass spectrometry, and its application to cardiovascular research.
Biomed. Chromatogr. 28(6) , 913-7, (2014) The accurate and specific measurement of vitamin D is increasingly important for determining the role of vitamin D in the pathogenesis of disease. Liquid chromatography coupled to tandem mass spectrometry (LC/MS/MS) has increasingly become the analytical moda... |
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25-hydroxvitamin D3 promotes the long-term effect of specific immunotherapy in a murine allergy model.
J. Immunol. 193(3) , 1017-23, (2014) Calcitriol (1α,25-dihydroxyvitamin D3) is the active vitamin D metabolite and mediates immunological functions, which are relevant in allergy. Its therapeutic use is limited by hypercalcaemic toxicity. We have previously shown that the activation of the vitam... |
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Vitamin D3 metabolite calcidiol primes human dendritic cells to promote the development of immunomodulatory IL-10-producing T cells.
Vaccine 32(47) , 6294-302, (2014) Vitamin D is recognized as a potent immunosuppressive drug. The suppressive effects of vitamin D are attributed to its physiologically active metabolite 1,25 dihydroxy vitamin D3 (calcitriol), which was shown, to prime dendritic cells (DCs) to promote the dev... |
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Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells.
J. Immunol. 195 , 96-104, (2015) The localization of memory T cells to human skin is essential for long-term immune surveillance and the maintenance of barrier integrity. The expression of CCR8 during naive T cell activation is controlled by skin-specific factors derived from epidermal kerat... |
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Quantification of neurosteroids during pregnancy using selective ion monitoring mass spectrometry.
Steroids 95 , 24-31, (2015) Analytical techniques used to quantify neurosteroids in biological samples are often compromised by non-specificity and limited dynamic range which can result in erroneous results. A relatively rapid and inexpensive gas chromatography-mass spectrometry (GC-MS... |
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[Severe hypercalcemia after substitution of prolonged deficiency of vitamin D in a patient with primary hyperparathyroidism].
Presse Med. 43(12 Pt 1) , 1391-4, (2014)
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Local Sustained Delivery of 25-Hydroxyvitamin D3 for Production of Antimicrobial Peptides.
Pharm. Res. 32 , 2851-62, (2015) This study seeks to develop fiber membranes for local sustained delivery of 25-hydroxyvitamin D3 to induce the expression and secretion of LL-37 at or near the surgical site, which provides a novel therapeutic approach to minimize the risk of infections.25-hy... |
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Common variants in CYP2R1 and GC genes are both determinants of serum 25-hydroxyvitamin D concentrations after UVB irradiation and after consumption of vitamin D₃-fortified bread and milk during winter in Denmark.
Am. J. Clin. Nutr. 101(1) , 218-27, (2015) Little is known about how the genetic variation in vitamin D modulating genes influences ultraviolet (UV)B-induced 25-hydroxyvitamin D [25(OH)D] concentrations. In the Food with vitamin D (VitmaD) study, we showed that common genetic variants rs10741657 and r... |