2-Amino-4-chloro-5-nitrophenol

2-Amino-4-chloro-5-nitrophenol Structure
2-Amino-4-chloro-5-nitrophenol structure
Common Name 2-Amino-4-chloro-5-nitrophenol
CAS Number 6358-07-2 Molecular Weight 188.568
Density 1.7±0.1 g/cm3 Boiling Point 402.4±45.0 °C at 760 mmHg
Molecular Formula C6H5ClN2O3 Melting Point 225ºC
MSDS Chinese USA Flash Point 197.2±28.7 °C
Symbol GHS07
GHS07
Signal Word Warning

Design, synthesis, and biological evaluation of achiral analogs of duocarmycin SA.

Bioorg. Med. Chem. Lett. 15(1) , 177-80, (2005)

The design, synthesis, as well as biochemical and biological evaluation of two novel achiral analogs of duocarmycin SA (DUMSA), 1 and 2, are described. Like CC-1065 and adozelesin, compounds 1 and 2 covalently reacted with adenine-N3 in AT-rich sequences and ...