(Rac)-Hesperetin
(Rac)-Hesperetin structure
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Common Name | (Rac)-Hesperetin | ||
|---|---|---|---|---|
| CAS Number | 69097-99-0 | Molecular Weight | 302.27900 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C16H14O6 | Melting Point | 227 - 232 °C | |
| MSDS | USA | Flash Point | N/A | |
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Hesperetin inhibit adipocyte differentiation and enhance Bax- and p21-mediated adipolysis in human mesenchymal stem cell adipogenesis.
J. Biochem. Mol. Toxicol. 29(3) , 99-108, (2015) We aimed to explore the antiadipogenic and adipolysis effect of hesperetin in human mesenchymal stem cells (hMSCs)-induced adipogenesis. IC50 value of hesperetin was higher for hMSCs such as 149.2 ± 13.2 μmol for 24 h and 89.4 ± 11.4 μmol in 48 h, whereas in ... |
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Enzyme-assisted extraction enhancing the phenolic release from cauliflower (Brassica oleracea L. var. botrytis) outer leaves.
J. Agric. Food Chem. 62(30) , 7468-76, (2014) Phenolic compounds are highly present in byproducts from the cauliflower (Brassica oleracea L. var. botrytis) harvest and are thus a valuable source for valorization toward phenolic-rich extracts. In this study, we aimed to optimize and characterize the relea... |
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Flavonoid composition and antioxidant activities of Chinese local pummelo (Citrus grandis Osbeck.) varieties.
Food Chem. 161 , 230-8, (2014) China is one of the most important diversity centres of the genus Citrus L. and is particularly rich in pummelo germplasm. In this study, the flavonoids in the peels and pulps of 28 Chinese local pummelos and four grapefruits were determined by optimised Ultr... |
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Ingredients in fruit juices interact with dasatinib through inhibition of BCRP: a new mechanism of beverage-drug interaction.
J. Pharm. Sci. 104(1) , 266-75, (2014) Small molecule tyrosine kinase inhibitors (TKIs) are a group of highly novel and target-specific anticancer drugs. Recently, most TKIs are found to be substrates of P-glycoprotein (P-gp) and Breast Cancer Resistance Protein (BCRP). However, little information... |
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Amino acid, mineral, and polyphenolic profiles of black vinegar, and its lipid lowering and antioxidant effects in vivo.
Food Chem. 168 , 63-9, (2014) Black vinegar (BV) contains abundant essential and hydrophobic amino acids, and polyphenolic contents, especially catechin and chlorogenic acid via chemical analyses. K and Mg are the major minerals in BV, and Ca, Fe, Mn, and Se are also measured. After a 9-w... |
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In vitro and in silico studies to explore structural features of flavonoids for aldehyde oxidase inhibition.
Arch. Pharm. (Weinheim) 347(10) , 738-47, (2014) Aldehyde oxidase (AO), an important enzyme in the biotransformation of drugs and xenobiotics, is inhibited by flavonoids. This enzyme can metabolize both aldehydes and N-heterocycles. In this work, a set of 15 flavonoids was assessed for inhibitory activity o... |
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Liquid chromatography-tandem mass spectrometry assay for the simultaneous quantification of simvastatin, lovastatin, atorvastatin, and their major metabolites in human plasma.
J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 983-984 , 18-25, (2015) Millions of individuals are treated with a variety of statins that are metabolized to a variety of active metabolites. A single assay capable of simultaneously quantifying commonly used statins and their major metabolites has not been previously reported. Her... |
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Strategies for differentiation of isobaric flavonoids using liquid chromatography coupled to electrospray ionization mass spectrometry.
J. Mass Spectrom. 49(7) , 646-63, (2014) Flavonoids are a class of secondary plant metabolites existing in great variety in nature. Due to this variety, identification can be difficult, especially as overlapping compounds in both chromatographic separations and mass spectrometric detection are commo... |
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Optimization of microwave-assisted extraction of polyphenols from herbal teas and evaluation of their in vitro hypochlorous acid scavenging activity.
J. Agric. Food Chem. 62(46) , 11109-15, (2014) Hypochlorous acid (HOCl) is an important reactive oxygen species (ROS) and non-radical and is taking part in physiological processes concerned with the defense of the organism, but there has been limited information regarding its scavenging by polyphenols. Th... |
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Apigenin inhibits enterovirus-71 infection by disrupting viral RNA association with trans-acting factors.
PLoS ONE 9(10) , e110429, (2014) Flavonoids are widely distributed natural products with broad biological activities. Apigenin is a dietary flavonoid that has recently been demonstrated to interact with heterogeneous nuclear ribonucleoproteins (hnRNPs) and interferes with their RNA editing a... |