Tyloxapol
Tyloxapol structure
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Common Name | Tyloxapol | ||
|---|---|---|---|---|
| CAS Number | 25301-02-4 | Molecular Weight | 261.38 (monomer) | |
| Density | 1.1 | Boiling Point | 282.3ºC at 760 mmHg | |
| Molecular Formula | (C15H21O(C2H4O)m)n | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 148.3ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Filtration improves the performance of a high-throughput screen for anti-mycobacterial compounds.
PLoS ONE 9(5) , e96348, (2014) The tendency for mycobacteria to aggregate poses a challenge for their use in microplate based assays. Good dispersions have been difficult to achieve in high-throughput screening (HTS) assays used in the search for novel antibacterial drugs to treat tubercul... |
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The effects of the decaffeination of coffee samples on platelet aggregation in hyperlipidemic rats.
Plant Foods Hum. Nutr. 68(3) , 268-73, (2013) The effect of coffee on cardiovascular diseases is still controversial. It is known that the process of decaffeination may influence the chemical constitution and, therefore, the biological effects of coffee. This study thus evaluated the effects of decaffein... |
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Surfactant blocks lipopolysaccharide signaling by inhibiting both NFκB and PARP activation in experimental ARDS.
Mol. Cell Biochem. 354(1-2) , 113-22, (2011) Surfactant plays an important role in lung homeostasis and is also involved in maintaining innate immunity within the lung. Lipopolysaccharide (LPS) is known to elicit acute proinflammatory responses in lung diseases such as acute respiratory distress syndrom... |
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Postprandial changes in high density lipoproteins in rats subjected to gavage administration of virgin olive oil.
PLoS ONE 8(1) , e55231, (2013) The present study was designed to verify the influence of acute fat loading on high density lipoprotein (HDL) composition, and the involvement of liver and different segments of small intestine in the changes observed.To address these issues, rats were admini... |
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Hypolipidaemic activity of orally administered diphenyl diselenide in Triton WR-1339-induced hyperlipidaemia in mice.
J. Pharm. Pharmacol. 61(12) , 1673-9, (2009) A significant association between the trace element selenium and hypercholesterolaemia has been reported. This study was designed to investigate a potential hypolipidaemic effect of diphenyl diselenide ((PhSe)(2)) in Triton WR-1339-induced hyperlipidaemia in ... |
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In vivo antihyperlipidemic activity of a new series of N-(benzoylphenyl) and N-(acetylphenyl)-1-benzofuran-2-carboxamides in rats.
Arch. Pharm. (Weinheim) 345(5) , 401-6, (2012) A new series of N-(benzoylphenyl) and N-(acetylphenyl)-1-benzofuran-2-carboxamides (3a-3d and 4a'-4c') were synthesized. Compounds (3a, 3b, and 4a'-4c') were tested in vivo using Triton-WR-1339-induced hyperlipidemic rats as an experimental model for their hy... |
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Pregnane glycoside from Hemidesmus indicus as a potential anti-oxidant and anti-dyslipidemic agent.
Nat. Prod. Res. 24(15) , 1371-8, (2010) A new pregnane glycoside hindicusine (1) was isolated from the CHCl(3)-EtOH (3 : 2) extract of Hemidesmus indicus, whose structure was established on the basis of spectroscopic studies. The glycoside (1) and its acetylated derivative (5) were evaluated for th... |
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The hypolipidemic activity of novel benzofuran-2-carboxamide derivatives in Triton WR-1339-induced hyperlipidemic rats: a comparison with bezafibrate.
J. Enzyme Inhib. Med. Chem. 25(6) , 751-5, (2010) Using Triton WR-1339-induced hyperlipidemic rats as an experimental model, we investigated whether compound 4 [N-(9,10-dihydro-9,10-dioxoanthracen-2-yl)benzofuran-2-carboxamide] and compound 5 [N-(4-benzoylphenyl)benzofuran-2-carboxamide], two novel anti-hype... |
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Lack of plasma albumin impairs intravascular lipolysis and explains the associated free fatty acids deficiency and hypertriglyceridemia.
Lipids Health Dis. 9 , 146, (2010) Abnormalities in lipid metabolism and transport are hallmarks in analbuminemic Nagase rats (NAR) and humans. Triglyceridemia is nearly 3- to 5-fold higher in female NAR than in control Sprague-Dawley rats (SDR). Also, NAR present with a severe plasma free fat... |
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Hypolipidemic activity of Symplocos cochinchinensis S. Moore leaves in hyperlipidemic rats.
J. Nat. Med. 66(1) , 32-8, (2012) The hypolipidemic activity of Symplocos cochinchinensis S. Moore leaves was studied in Triton WR-1339- and high fat diet-induced hyperlipidemic rats. In Triton WR-1339-induced hyperlipidemic rats, the hexane extract (250 and 500 mg/kg) exerted a significant (... |