2,6-Dibromo-4-fluoroaniline

2,6-Dibromo-4-fluoroaniline Structure
2,6-Dibromo-4-fluoroaniline structure
Common Name 2,6-Dibromo-4-fluoroaniline
CAS Number 344-18-3 Molecular Weight 268.909
Density 2.1±0.1 g/cm3 Boiling Point 265.2±35.0 °C at 760 mmHg
Molecular Formula C6H4Br2FN Melting Point 64-66 °C(lit.)
MSDS Chinese USA Flash Point 114.2±25.9 °C
Symbol GHS07
GHS07
Signal Word Warning

Asymmetric synthesis of a prostaglandin D2 receptor antagonist.

J. Org. Chem. 70(1) , 268-74, (2005)

An asymmetric synthesis was developed for the production of a prostaglandin D(2) receptor antagonist for the treatment of allergic rhinitis. The stereogenic center was set using asymmetric allylic alkylation chemistry, and the core of the structure was constr...