1-isocyanatodecane

1-isocyanatodecane Structure
1-isocyanatodecane structure
Common Name 1-isocyanatodecane
CAS Number 1191-69-1 Molecular Weight 183.29100
Density 0.880 g/mL at 25ºC(lit.) Boiling Point 85-89ºC(lit.)
Molecular Formula C11H21NO Melting Point N/A
MSDS Chinese USA Flash Point 195 °F
Symbol GHS07 GHS08
GHS07, GHS08
Signal Word Danger

Discovery of a potent and highly β1 specific proteasome inhibitor from a focused library of urea-containing peptide vinyl sulfones and peptide epoxyketones.

Org. Biomol. Chem. 10(1) , 181-94, (2012)

Syringolins, a class of natural products, potently and selectively inhibit the proteasome and show promising antitumour activity. To gain insight in the mode of action of syringolins, the ureido structural element present in syringolins is incorporated in oli...