Lycorine chloride
Lycorine chloride structure
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Common Name | Lycorine chloride | ||
|---|---|---|---|---|
| CAS Number | 2188-68-3 | Molecular Weight | 323.77 | |
| Density | N/A | Boiling Point | 477.4ºC at 760 mmHg | |
| Molecular Formula | C16H18ClNO4 | Melting Point | 210-212ºC | |
| MSDS | Chinese USA | Flash Point | 242.5ºC | |
| Symbol |
GHS06 |
Signal Word | Danger | |
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Comparison of anti-acetylcholinesterase activity of bulb and leaf extracts of Sternbergia candida Mathew & T. Baytop.
Acta Biol. Hung. 65(4) , 396-404, (2014) Studies on Alzheimer's disease have been highlighted due to increasing prevalence of this disease. Oldest hypothesis about the pathophysiology strengthens the research of cholinesterase inhibitors for treatment. Amaryllidaceae plants are well known for alkalo... |
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[Study on the chemical constituents from the bulbs of Zephyranthes candida].
Zhong Yao Cai 33(11) , 1730-2, (2010) To study the chemical constituents from the bulbs of Zephyranthes candida.The chemical constituents were separated and purified by means of several chromatographies and their structures were elucidated by spectroscopic methods.Six compounds were isolated and ... |
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Copper-induced synthesis of ascorbate, glutathione and phytochelatins in the marine alga Ulva compressa (Chlorophyta).
Plant Physiol. Biochem. 51 , 102-8, (2012) In order to analyze the synthesis of antioxidant and heavy metal-chelating compounds in response to copper stress, the marine alga Ulva compressa (Chlorophyta) was exposed to 10 μM copper for 7 days and treated with inhibitors of ASC synthesis, lycorine, and ... |
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Simultaneous quantification of Amaryllidaceae alkaloids from Zephyranthes grandiflora by UPLC-DAD/ESI-MS/MS.
J. Pharm. Biomed. Anal. 71 , 187-92, (2012) A rapid, simple and sensitive ultra performance liquid chromatography-diode array detection method (UPLC-DAD) was developed and validated for quantification of four biologically important Amaryllidaceae alkaloids viz. lycoramine, hamayne, haemanthamine and to... |
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Metabolic studies of theAmaryllidaceousalkaloids galantamine and lycorine based on electrochemical simulation in addition toin vivoandin vitromodels
Anal. Chim. Acta 756 , 60-72, (2012) Graphical abstract |
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Acetylcholinesterase inhibition within the lycorine series of Amaryllidaceae alkaloids.
Nat. Prod. Commun. 7(7) , 959-62, (2012) The plant family Amaryllidaceae occupies a privileged status within the botanical hierarchy due to its horticultural and ornamental appeal, as well as its widespread usage in the traditional medicinal practices of indigenous peoples across the globe. Of great... |
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Lycorine induces cell death in the amitochondriate parasite, Trichomonas vaginalis, via an alternative non-apoptotic death pathway.
Phytochemistry 72(7) , 645-50, (2011) In this study, the mechanism of action of the pro-apoptotic alkaloid lycorine on an amitochondriate cell, the parasite Trichomonas vaginalis, was investigated. The cytotoxicity of lycorine against T. vaginalis was studied from 2.5 to 1000μM and several import... |
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Activity of lycorine analogues against the fish bacterial pathogen Flavobacterium columnare.
J. Agric. Food Chem. 59(11) , 5977-85, (2011) In a continuing effort to discover natural products and natural product-based compounds for the control of columnaris disease in channel catfish (Ictalurus punctatus), 17 lycorine analogues were synthesized, including new benzoyl analogues 6-16, and evaluated... |
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Kinetic study of the rearrangement of deuterium-labeled 4'-O-methylnorbelladine in Leucojum aestivum shoot cultures by mass spectrometry. Influence of precursor feeding on amaryllidaceae alkaloid accumulation.
J. Nat. Prod. 74(11) , 2356-61, (2011) Alkaloids from plants of the family Amaryllidaceae have important pharmacological properties and can be regarded as derivatives of the common precursor 4'-O-methylnorbelladine (6) via intramolecular oxidative phenol coupling. Their biosynthetic pathway, parti... |
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In vivo assessment of antiemetic drugs and mechanism of lycorine-induced nausea and emesis.
Arch. Toxicol. 85(12) , 1565-73, (2011) Lycorine is the main alkaloid of many Amaryllidaceae and known to cause poisoning with still unknown mechanisms. Longer lasting toxicological core symptoms of nausea and emesis may become a burden for human and animal patients and may result in substantial lo... |