1,3-Propanediamine,N1-(2-chloroethyl)-N3-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride (1:2)
1,3-Propanediamine,N1-(2-chloroethyl)-N3-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride (1:2) structure
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Common Name | 1,3-Propanediamine,N1-(2-chloroethyl)-N3-(6-chloro-2-methoxy-9-acridinyl)-, hydrochloride (1:2) | ||
|---|---|---|---|---|
| CAS Number | 17070-45-0 | Molecular Weight | 451.21700 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C19H23Cl4N3O | Melting Point | 261-262ºC | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS06, GHS08 |
Signal Word | Danger | |
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Toxicologic evaluation of Dichrostachys glomerata extract: subchronic study in rats and genotoxicity tests.
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Genotoxicity of rice bran oil extracted by supercritical CO2 extraction.
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Attenuation of acridine mutagen ICR-191--DNA interactions and DNA damage by the mutagen interceptor chlorophyllin.
Biophys. Chem. 135(1-3) , 69-75, (2008) We have investigated the ability of chlorophyllin (CHL) to interact with acridine mutagen ICR-191 (2-methoxy-6-chloro-9-(3-(2-chloroethyl)aminopropylamino)acridine) and also its ability to decrease binding of ICR-191 to DNA in a simple three-component competi... |
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Effects of the umuDC, mucAB, and samAB operons on the mutational specificity of chemical mutagenesis in Escherichia coli: II. Base substitution mutagenesis.
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Specificity of base substitutions induced by the acridine mutagen ICR-191: mispairing by guanine N7 adducts as a mutagenic mechanism.
Genetics 129(4) , 981-9, (1991) As the most nucleophilic site in DNA, the guanine N7 atom is a major site of adduction by a large number of alkylating mutagens and carcinogens. Aflatoxin B1, a powerful mutagen, is believed to act through its reaction with this DNA site. On the basis of the ... |
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A novel bacterial reversion and forward mutation assay based on green fluorescent protein.
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Acridine mutagenesis of zebrafish (Danio rerio).
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Induced mutation spectra at the upp locus in Salmonella typhimurium: response of the target gene in the FU assay to mechanistically different mutagens.
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