Eslicarbazepine acetate

Eslicarbazepine acetate Structure
Eslicarbazepine acetate structure
Common Name Eslicarbazepine acetate
CAS Number 236395-14-5 Molecular Weight 296.320
Density 1.3±0.1 g/cm3 Boiling Point 427.4±55.0 °C at 760 mmHg
Molecular Formula C17H16N2O3 Melting Point 183-185ºC
MSDS Chinese USA Flash Point 212.3±31.5 °C
Symbol GHS07
GHS07
Signal Word Warning

Interaction of the novel anticonvulsant, BIA 2-093, with voltage-gated sodium channels: comparison with carbamazepine.

Epilepsia 42 , 600-608, (2001)

BIA 2-093 [(S)-(-)-10-acetoxy-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide] is endowed with an anticonvulsant potency similar to that of carbamazepine (CBZ), but produces less cognitive and motor impairment. This study evaluated whether voltage-gated sod...

The novel anticonvulsant BIA 2-093 inhibits transmitter release during opening of voltage-gated sodium channels: a comparison with carbamazepine and oxcarbazepine.

Neurochem. Int. 40 , 435-440, (2002)

(S)-(-)-10-acetoxy-10,11-dihydro-5H-dibenz/b,f/azepine-5-carboxamide (BIA 2-093) is endowed with high anticonvulsant activity and shares with carbamazepine (CBZ) and oxcarbazepine (OXC) the capability to inhibit voltage-gated sodium channels (VGSC). The prese...