N-Hydroxy-N'-(3-pyridinyl)octanediamide

N-Hydroxy-N'-(3-pyridinyl)octanediamide Structure
N-Hydroxy-N'-(3-pyridinyl)octanediamide structure
Common Name N-Hydroxy-N'-(3-pyridinyl)octanediamide
CAS Number 382180-17-8 Molecular Weight 265.308
Density 1.2±0.1 g/cm3 Boiling Point N/A
Molecular Formula C13H19N3O3 Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Evaluation of histone deacetylase inhibitors (HDACi) as therapeutic leads for human African trypanosomiasis (HAT).

Bioorg. Med. Chem. 23 , 5151-5, (2015)

Two of the histone deacetylases, TbDAC1 and TbDAC3, have been reported to be essential genes in trypanosomes. Therefore, we tested the activity of a panel of human histone deacetylase inhibitors (HDACi) for their ability to block proliferation of Trypanosoma ...