1,12-Diaminododecane
1,12-Diaminododecane structure
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Common Name | 1,12-Diaminododecane | ||
|---|---|---|---|---|
| CAS Number | 2783-17-7 | Molecular Weight | 200.364 | |
| Density | 0.9±0.1 g/cm3 | Boiling Point | 274.9±8.0 °C at 760 mmHg | |
| Molecular Formula | C12H28N2 | Melting Point | 67-69 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 155.0±0.0 °C | |
| Symbol |
GHS05, GHS07 |
Signal Word | Danger | |
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Antitubercular activity of alpha,omega-diaminoalkanes, H2N(CH2)nNH2.
Bioorg. Med. Chem. Lett. 19 , 4937-8, (2009) A series of 11 alpha,omega-diaminoalkanes, (H(2)N(CH(2))(n)NH(2), n=2-12) have been evaluated for their in vitro antibacterial activity against Mycobacterium tuberculosis H37Rv. Compounds, (H(2)N(CH(2))(n)NH(2), n=9-12), exhibited a very good activities in th... |
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A label-free impedimetric immunosensor for direct determination of the textile dye Disperse Orange 1.
Talanta 142 , 183-9, (2015) A strategy for a label-free impedimetric immunosensor is described for detection of the textile dye Disperse Orange 1 (DO1). The compounds 1,12-diaminododecane (DADD) and then 1,7-diaminoheptane (DAH) were firstly successively grafted onto a glassy carbon ele... |
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Design, RNA cleavage and antiviral activity of new artificial ribonucleases derived from mono-, di- and tripeptides connected by linkers of different hydrophobicity.
Bioorg. Med. Chem. 24 , 1346-55, (2016) A novel series of metal-free artificial ribonucleases (aRNases) was designed, synthesized and assessed in terms of ribonuclease activity and ability to inactivate influenza virus WSN/A33/H1N1 in vitro. The compounds were built of two short peptide fragments, ... |
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Mechanism of charging and supercharging molecules in electrospray ionization.
J. Am. Chem. Soc. 125(8) , 2319-27, (2003) The origin of the extent of charging and the mechanism by which multiply charged ions are formed in electrospray ionization have been hotly debated for over a decade. Many factors can affect the number of charges on an analyte ion. Here, we investigate the ex... |
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Long chain diamines inhibit growth of C6 glioma cells according to their hydrophobicity. An in vitro and molecular modeling study.
Naunyn Schmiedebergs Arch. Pharmacol. 361(3) , 235-46, (2000) A series of diamines with the general structure NH2(CH2)xNH2, x=2-12, was tested for their potential effects on cell proliferation of cultured rat C6 glioma cells in comparison to natural polyamines. Long chain diamines reduced cell number after 48 h in cultu... |
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Stabilization of human prostatic acid phosphatase by cross-linking with diamines.
Biochem. Int. 6(5) , 627-33, (1983) The acid phosphatase [EC 3.1.3.2] from human prostate gland is very unstable glycoprotein. To stabilize the enzyme cross-linking reaction with diamines was adopted. The carboxyl groups of the enzyme were activated with 1-ethyl-(3-dimethylaminopropyl)-carbodii... |
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Layer-by-layer growth of CdSe-based nanocrystal light-emitting diodes.
J. Nanosci. Nanotechnol. 1(1) , 59-64, (2001) The partial exchange of surface-passivating trioctylphosphine oxide (TOPO) on CdSe and ZnS-clad CdSe (CdSe/ZnS) nanocrystals with primary amines was utilized to grow ultra-thin films of these nanocrystals under nonaqueous conditions. This growth was achieved ... |
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Aggregation behavior of an amino acid-derived bolaamphiphile and a conventional surfactant mixed system.
J. Colloid. Interface Sci. 336(2) , 766-72, (2009) The aggregation behavior of a mixed system consisting of a novel histidine-derived bolaamphiphile 1,12-dihistidine diaminododecane (H(2)D) and the conventional surfactant dodecyltrimethylammonium bromide (DTAB) has been investigated. The microstructure of the... |
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End-to-end correlation for a C-12 hydrocarbon chain.
J. Magn. Reson. 160(2) , 161-5, (2003) The 19F nuclear spin-lattice relaxation rate constants were measured as a function of magnetic field strength for 1,12-diaminododecane labeled at one end with a nitroxide radical and at the other with a trifluoromethyl group. The magnetic relaxation dispersio... |
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Inhalation toxicology of fumed dodecanediamine.
Inhal. Toxicol. 16(10) , 721-9, (2004) Dodecanediamine (DDDA) is used in the production of specialty polymers. Exposure to this chemical was associated with dermal sensitization in pilot-plant workers, and the possibility that the chemical could produce dermal sensitization was confirmed in a guin... |