4-chlorobenzeneethanamine
4-chlorobenzeneethanamine structure
|
Common Name | 4-chlorobenzeneethanamine | ||
|---|---|---|---|---|
| CAS Number | 156-41-2 | Molecular Weight | 155.625 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 233.4±15.0 °C at 760 mmHg | |
| Molecular Formula | C8H10ClN | Melting Point | N/A | |
| MSDS | USA | Flash Point | 106.1±0.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
|
Dopamine beta-hydroxylase: activity and inhibition in the presence of beta-substituted phenethylamines.
Biochemistry 21(1) , 67-75, (1982)
|
|
|
Use of alternate substrates to probe the order of substrate addition to dopamine beta-hydroxylase.
Arch. Biochem. Biophys. 249(1) , 70-5, (1986) In order to determine the order of substrate binding to dopamine beta-hydroxylase during catalysis, the effect of alternate substrates upon kinetic parameters was examined. The V/K value for ascorbate was unchanged when tyramine, phenylpropylamine, p-Cl-phene... |
|
|
Comparative effects of various serotonin releasing agents in mice.
Biochem. Pharmacol. 29(23) , 3163-7, (1980)
|
|
|
A pyrazolopyran derivative preferentially inhibits the activity of human cytosolic serine hydroxymethyltransferase and induces cell death in lung cancer cells.
Oncotarget 7 , 4570-83, (2016) Serine hydroxymethyltransferase (SHMT) is a central enzyme in the metabolic reprogramming of cancer cells, providing activated one-carbon units in the serine-glycine one-carbon metabolism. Previous studies demonstrated that the cytoplasmic isoform of SHMT (SH... |
|
|
Neuropharmacology of the parasitic trematode, Schistosoma mansoni.
Am. J. Trop. Med. Hyg. 32(1) , 83-93, (1983) Neuropharmacological studies of Schistosoma mansoni were conducted in vitro using visual observations of motor activity and measurements of worm length and extracellular electrical activity. The instrumentation and methodology described quantitatively measure... |
|
|
Para-chlorophenylethylamine in brains of rats treated with a monoamine oxidase inhibitor and p-chlorophenylalanine.
Prog. Neuropsychopharmacol. Biol. Psychiatry 6(4-6) , 343-6, (1982) 1. The accumulation of p-chlorophenylethylamine (pCPE) in rat brain after administration of pargyline plus p-chlorophenylalanine (pCPA) is demonstrated. 2. Measurements of pCPE in brain were performed at 0.25 h, 1 h and 4 h after administration of pCPA to par... |
|
|
Harmane inhibits serotonergic dorsal raphe neurons in the rat.
Psychopharmacology 182(4) , 562-9, (2005) Harmane and norharmane (two beta-carbolines) are tobacco components or products. The effects of harmane and norharmane on serotonergic raphe neurons remain unknown. Harmane and norharmane are inhibitors of the monoamine oxidases A (MAO-A) and B (MAO-B), respe... |
|
|
The role of serotonin release and autoreceptors in the dorsalis raphe nucleus in the control of serotonin release in the cat caudate nucleus.
Neuroscience 39(3) , 639-47, (1990) Using a push-pull cannula technique and an isotopic method for estimating [3H]serotonin continuously synthesized from [3H]tryptophan, the effects of changes in the release of serotonin in the dorsalis raphe nucleus on in vivo release of [3H]serotonin in the c... |
|
|
Mitochondrial damage induced by fetal hyperphenylalaninemia in the rat brain and liver: its prevention by melatonin, Vitamin E, and Vitamin C.
Neurosci. Lett. 392(1-2) , 1-4, (2006) Abnormal oxidative stress was observed in hyperphenylalaninemia and other inborn errors of intermediary metabolism, owing to the accumulation of toxic metabolites, free radical production and increased LPO products. In our model of maternal hyperphenylalanine... |
|
|
Comparative effects of substituted phenylethylamines on brain serotonergic mechanisms.
J. Pharmacol. Exp. Ther. 213(2) , 254-60, (1980) A series of substituted phenylethylamines were examined for their relative potencies to 1) release and inhibit accumulation of labeled serotonin in brain synaptosomes, 2) compete with serotonin receptor binding and 3) induce the "serotonin syndrome" in mice. ... |