Tiamulin Fumarate

Tiamulin Fumarate Structure
Tiamulin Fumarate structure
Common Name Tiamulin Fumarate
CAS Number 55297-96-6 Molecular Weight 609.814
Density N/A Boiling Point 563ºCat 760 mmHg
Molecular Formula C32H51NO8S Melting Point 147-148°C
MSDS Chinese USA Flash Point 294.3ºC
Symbol GHS07
GHS07
Signal Word Warning

Mutations in the 50S ribosomal subunit of Brachyspira hyodysenteriae associated with altered minimum inhibitory concentrations of pleuromutilins.

Vet. Microbiol. 172(1-2) , 223-9, (2014)

Brachyspira hyodysenteriae, the causative agent of swine dysentery, is responsible for severe mucohaemorrhagic colitis with considerable financial loss to worldwide swine production. Antimicrobial resistance against macrolides and lincosamides is widespread a...

[Effect of different compatibility of tetramethylpyrazine on its pharmacokinetics in vivo].

Zhongguo Zhong Yao Za Zhi 37(9) , 1311-4, (2012)

To study the pharmacokinetics of single administration and different compatibility of tetramethylpyrazine (TMP) in rats.Thirty two Sprague-Dawley rats were randomly divided into 4 groups: the TMP (30 mg x kg(-1)) group, the TMP+FA (30 mg x kg(-1) + 50 mg x kg...

Design, synthesis, and antibacterial activity of novel pleuromutilin derivatives bearing an amino thiazolyl ring.

Arch. Pharm. (Weinheim) 345(8) , 638-46, (2012)

A series of novel pleuromutilin derivatives containing the amino thiazolyl ring were designed, synthesized, and evaluated for their antibacterial activities in vitro against Gram-positive clinical bacteria. All the target compounds showed better aqueous solub...

Simultaneous determination of three classes of antibiotics in the suspended solids of swine wastewater by ultrasonic extraction, solid-phase extraction and liquid chromatography-mass spectrometry.

J. Environ. Sci. (China) 23(10) , 1729-37, (2011)

This work describes a systematic approach to the development of a method for simultaneous determination of three classes of veterinary antibiotics in the suspended solids (SS) of swine wastewater, including five sulfonamides, three tetracyclines and one macro...

Mutations in 23S rRNA gene associated with decreased susceptibility to tiamulin and valnemulin in Mycoplasma gallisepticum.

FEMS Microbiol. Lett. 308(2) , 144-9, (2010)

Mycoplasma gallisepticum is a major etiological agent of chronic respiratory disease (CRD) in chickens and sinusitis in turkeys. The pleuromutilin antibiotics tiamulin and valnemulin are currently used in the treatment of M. gallisepticum infection. We studie...

Compatibility of a combination of tiamulin and chlortetracycline with salinomycin in feed during a pulsed medication program coadministration in broilers.

Poult. Sci. 87(12) , 2528-34, (2008)

In an earlier study, the continuous medication of broiler feed with a combination of tiamulin (TIA; 20 mg/kg), chlortetracycline (CTC; 60 mg/kg), and the ionophore anticoccidial salinomycin (SAL; 60 mg/kg) caused an initial increase in BW and feed efficiency ...

Factors influencing the activity of tiamulin against Histomonas meleagridis in vitro.

Avian Dis. 54(2) , 936-8, (2010)

In this study, we investigated the activity of tiamulin fumerate against three strains of Histomonas meleagridis in vitro under different conditions. Tiamulin reduced histomonal growth of all three strains at concentrations of 20 ppm and higher. Cultures in p...

Tiamulin hydrogen fumarate--veterinary uses and HPLC method of determination in premixes and medicated feeding stuffs.

Acta Pol. Pharm. 67(6) , 682-5, (2010)

Decreased susceptibility of MRSA ST398 to tiamulin.

Vet. Microbiol. 151(3-4) , 422-3, (2011)

Spironucleosis in gamebirds.

Vet. Rec. 164(12) , 377, (2009)