6-Aminopurine phosphate

6-Aminopurine phosphate Structure
6-Aminopurine phosphate structure
Common Name 6-Aminopurine phosphate
CAS Number 70700-30-0 Molecular Weight 233.122
Density N/A Boiling Point 553.5ºC at 760 mmHg
Molecular Formula C5H5N5 Melting Point 261-263ºC
MSDS N/A Flash Point 322.7ºC
Symbol GHS07
GHS07
Signal Word Warning

Disturbed Hsp70 and Hsp27 expression and thiol redox status in porcine kidney PK15 cells provoked by individual and combined ochratoxin A and citrinin treatments.

Food Chem. Toxicol. 71 , 97-105, (2014)

The aim of this study was to explore the oxidative properties of ochratoxin A (OTA) and citrinin (CTN) as a possible underlying mechanism of their individual and/or combined cytotoxicity. Metabolic activity of PK15 porcine kidney cells was significantly reduc...

Vegetables' juice influences polyol pathway by multiple mechanisms in favour of reducing development of oxidative stress and resultant diabetic complications.

Pharmacogn. Mag. 10(Suppl 2) , S383-91, (2014)

Hyperglycemia induced generation of free radicals and consequent development of oxidative stress by polyol pathway is one of the crucial mechanisms stirring up development of diabetic complications. We evaluated influence of ten vegetables' juice on polyol pa...

The traditional drug Gongjin-Dan ameliorates chronic fatigue in a forced-stress mouse exercise model.

J. Ethnopharmacol. 168 , 268-78, (2015)

Gongjin-Dan is a representative traditional Oriental medicine herbal drug that has been used to treat chronic fatigue symptoms for several hundred years. We evaluated the anti-fatigue effects of Gongjin-Dan and the underlying mechanisms in a chronic forced ex...

Spironolactone and dimethylsulfoxide effect on glucose metabolism and oxidative stress markers in polycystic ovarian syndrome rat model.

Exp. Clin. Endocrinol. Diabetes 122(3) , 154-62, (2014)

Because polycystic ovarian syndrome (PCOS) is a risk factor for type 2 diabetes, the affected women can present frequently prediabetic states such as impaired fasting glycaemia and/or impaired glucose tolerance. The purpose of our study is to explore the effe...

Changes in cellular energy allocation in Enchytraeus crypticus exposed to copper and silver--linkage to effects at higher level (reproduction).

Environ. Sci. Pollut. Res. Int. 22 , 14241-7, (2015)

Under stressful conditions, organisms often try to detoxify by mobilizing certain energy sources with costs to various functions, e.g. growth or reproduction. Cellular energy allocation (CEA) is a commonly used methodology to evaluate the energetic status of ...

Nano-Se attenuates cyclophosphamide-induced pulmonary injury through modulation of oxidative stress and DNA damage in Swiss albino mice.

Mol. Cell Biochem. 405 , 243-56, (2015)

Chemotherapy is an integral part of modern day treatment regimen but anticancer drugs fail to demarcate between cancerous and normal cells thereby causing severe form of systemic toxicity. Among which pulmonary toxicity is a dreadful complication developed in...

Point-of-Care Quantitative Measure of Glucose-6-Phosphate Dehydrogenase Enzyme Deficiency.

Pediatrics 136 , e1268-75, (2015)

Widespread newborn screening on a point-of-care basis could prevent bilirubin neurotoxicity in newborns with glucose-6-phosphate dehydrogenase (G6PD) deficiency. We evaluated a quantitative G6PD assay on a digital microfluidic platform by comparing its perfor...

Paroxetine decreased plasma exposure of glyburide partly via inhibiting intestinal absorption in rats.

Drug Metab. Pharmacokinet. 30 , 240-6, (2015)

Accumulating evidences have shown that diabetes is often accompanied with depression, thus it is possible that oral antidiabetic agent glyburide and antidepressive agent paroxetine are co-administered in diabetic patients. The aim of this study was to assess ...

Anti-oxidative and anti-inflammatory effects of lipoic acid in rat liver.

Microbiology 69 , 270-6, (2015)

Lipopolysaccharide (LPS) is a key inflammatory component of Gram-negative bacteria, which after entering the systemic circulation contributes to the development of septic hepatic failure.The aim of this study was to evaluate the effects of alpha lipoic acid (...

Metabolic characterization of meso-dihydroguaiaretic acid in liver microsomes and in mice.

Food Chem. Toxicol. 76 , 94-102, (2015)

meso-Dihydroguaiaretic acid (MDGA) is a major component of Myristica fragrans and Machilus thunbergii that is traditionally used as a spice and for medicinal purposes. Despite reports of various biological activities exerted by MDGA, there is no information r...