Dihydrotanshinone I
Dihydrotanshinone I structure
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Common Name | Dihydrotanshinone I | ||
|---|---|---|---|---|
| CAS Number | 87205-99-0 | Molecular Weight | 278.302 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 479.2±45.0 °C at 760 mmHg | |
| Molecular Formula | C18H14O3 | Melting Point | 214.0 to 218.0 °C | |
| MSDS | Chinese USA | Flash Point | 214.9±28.8 °C | |
| Symbol |
GHS07, GHS09 |
Signal Word | Warning | |
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Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function.
Sci. Rep. 5 , 16478, (2015) Post-transcriptional regulation is an essential determinant of gene expression programs in physiological and pathological conditions. HuR is a RNA-binding protein that orchestrates the stabilization and translation of mRNAs, critical in inflammation and tumor... |
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Comparison of neuroprotective effects of five major lipophilic diterpenoids from Danshen extract against experimentally induced transient cerebral ischemic damage.
Fitoterapia 83 , 1666-1674, (2012) We observed neuroprotective effects of five major lipophilic diterpenes derived from Danshen (Radix Salvia miltiorrhiza) extract, such as cryptotanshinone (CTs), dihydrotanshinone I (DTsI), tanshinone I (TsI), tanshinone IIA (TsIIA) and tanshinone IIB (TsIIB)... |
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Modeling gradient elution in countercurrent chromatography: efficient separation of tanshinones from Salvia miltiorrhiza Bunge.
J. Sep. Sci. 35 , 964-976, (2012) Countercurrent chromatography (CCC) is a support-free liquid-liquid chromatography using centrifugal fields to hold the liquid stationary phase. CCC has been widely applied in the separation of various natural and synthetic components using a variety of bipha... |
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Diterpenoid tanshinones and phenolic acids from cultured hairy roots of Salvia miltiorrhiza Bunge and their antimicrobial activities. Zhao J, Lou J, Mou Y, Li P, Wu J, Zhou L.
Molecules 3 , 2259-67, (2011)
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15,16-Dihydrotanshinone I, a Compound of Salvia miltiorrhiza Bunge, Induces Apoptosis through Inducing Endoplasmic Reticular Stress in Human Prostate Carcinoma Cells. Chuang MT, Ho FM, Wu CC, Zhuang SY, Lin SY, Suk FM, Liang YC.
Evid. Based. Complement. Alternat. Med. 2011 , (2011)
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Danshen extract 15,16-dihydrotanshinone I functions as a potential modulator against metabolic syndrome through multi-targeted pathways. Liu Q, Zhang Y, Lin Z, Shen H, Chen L, Hu L, Jiang H, Shen X.
J. Steroid Biochem. Mol. Biol. 4-5 , 155-63, (2010)
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