2-Chloro 5-chloromethylthiophene

2-Chloro 5-chloromethylthiophene Structure
2-Chloro 5-chloromethylthiophene structure
Common Name 2-Chloro 5-chloromethylthiophene
CAS Number 23784-96-5 Molecular Weight 167.056
Density 1.4±0.1 g/cm3 Boiling Point 215.9±0.0 °C at 760 mmHg
Molecular Formula C5H4Cl2S Melting Point 193-197°C
MSDS Chinese USA Flash Point 100.6±0.0 °C
Symbol GHS07
GHS07
Signal Word Warning

CYP19 (aromatase): exploring the scaffold flexibility for novel selective inhibitors.

Bioorg. Med. Chem. 16(18) , 8349-58, (2008)

Several derivatives out of a series of antifungal agents exhibited a good inhibitory potency against aromatase as well as a fairly good selectivity toward CYP17, even if lacking H-bond accepting substituents. Their common structural feature is a flexible back...