2,3-Naphthalenediol
2,3-Naphthalenediol structure
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Common Name | 2,3-Naphthalenediol | ||
|---|---|---|---|---|
| CAS Number | 92-44-4 | Molecular Weight | 160.17 | |
| Density | 1.3±0.1 g/cm3 | Boiling Point | 353.9±15.0 °C at 760 mmHg | |
| Molecular Formula | C10H8O2 | Melting Point | 161-165 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 181.0±15.0 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Phase II metabolism in human skin: skin explants show full coverage for glucuronidation, sulfation, N-acetylation, catechol methylation, and glutathione conjugation.
Drug Metab. Dispos. 43(1) , 126-39, (2014) Although skin is the largest organ of the human body, cutaneous drug metabolism is often overlooked, and existing experimental models are insufficiently validated. This proof-of-concept study investigated phase II biotransformation of 11 test substrates in fr... |
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The syntheses and characterizations of molybdenum(VI) complexes with catechol and 2,3-dihydroxynaphthalene, and the structure-effect relationship in their in vitro anticancer activities.
Dalton Trans. 41(28) , 8697-702, (2012) The reactions of (NH(4))(2)Mo(2)O(7)·2H(2)O with polyhydroxy phenols (catechol or 2,3-dihydroxynaphthalene) and ethylenediamine (en), trimethylenediamine (tn), 1,2-propanediamine (pn), triethylamine (Et(3)N) respectively, in the mixed-solvent of MeCN-EtOH-ami... |
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Selective antiproliferative activity of hydroxynaphthyl-beta-D-xylosides.
J. Med. Chem. 49 , 1932-8, (2006) The antiproliferative activity of the 14 isomeric monoxylosylated dihydroxynaphthalenes has been tested in vitro toward normal HFL-1 and 3T3 A31 cells as well as transformed T24 and 3T3 SV40 cells. The antiproliferative effect toward HFL-1 cells was correlate... |
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Reactions of linoleic acid peroxyl radicals with phenolic antioxidants: a pulse radiolysis study.
Int. J. Radiat. Biol. Relat. Stud. Phys. Chem. Med. 52(3) , 393-412, (1987) Linoleic acid peroxyl radicals (LOO.) can be viewed as model intermediates occurring during lipid peroxidation processes. Formation and reactions of these species were investigated in aqueous alkaline solution using the technique of pulse radiolysis combined ... |
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Hydrolytic metal with a hydrophobic periphery: titanium(IV) complexes of naphthalene-2,3-diolate and interactions with serum albumin.
Inorg. Chem. 47(18) , 8380-90, (2008) Serum albumin, the most abundant protein in human plasma (700 microM), binds diverse ligands at multiple sites. While studies have shown that serum albumin binds hard metals in chelate form, few have explored the trafficking of these metals by this protein. R... |
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A novel "pro-sensitizer" based sensing of enzymes using Tb(III) luminescence in a hydrogel matrix.
Chem. Commun. (Camb.) 48(38) , 4624-6, (2012) Chemically synthesized "pro-sensitizers" release the sensitizer in the presence of lipase or β-glucosidase, triggering a significant luminescence response from a lanthanide based hydrogel.This journal is © The Royal Society of Chemistry 2012 |
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The multidrug efflux regulator TtgV recognizes a wide range of structurally different effectors in solution and complexed with target DNA: evidence from isothermal titration calorimetry.
J. Biol. Chem. 280(21) , 20887-93, (2005) TtgV modulates the expression of the ttgGHI operon, which encodes an efflux pump that extrudes a wide variety of chemicals including mono- and binuclear aromatic hydrocarbons, aliphatic alcohols, and antibiotics of dissimilar chemical structure. Using a 'lacZ... |
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Regulation of rat liver phenylalanine hydroxylase. I. Kinetic properties of the enzyme's iron and enzyme reduction site.
J. Biol. Chem. 269 , 24637, (1994) Tetrahydropterins react with phenylalanine hydroxylase at a redox site, a regulatory site, and the catalytic site, but neither the properties of nor relationships among these sites are well understood. We have studied the redox site using the fluorescent iron... |
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Tris(spiroborate)-type anionic nanocycles.
Chem. Asian J. 7(7) , 1529-32, (2012) Full circle: New cyclic tris(spiroborate)s were prepared as molecular recognition modules for nanometer-sized cationic guests. These cyclophanes were simply prepared by treating corresponding bis(2,3-dihydroxynaphthalene)s with an equimolar amount of boric ac... |
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Redox cycling by cytochrome P-450.
Biochem. Soc. Trans. 25(4) , S579, (1997)
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