2-(Bromomethyl)acrylic acid

2-(Bromomethyl)acrylic acid Structure
2-(Bromomethyl)acrylic acid structure
Common Name 2-(Bromomethyl)acrylic acid
CAS Number 72707-66-5 Molecular Weight 164.985
Density 1.7±0.1 g/cm3 Boiling Point 268.8±23.0 °C at 760 mmHg
Molecular Formula C4H5BrO2 Melting Point 70-73 °C(lit.)
MSDS Chinese USA Flash Point 116.4±22.6 °C
Symbol GHS05
GHS05
Signal Word Danger

Folate analogues. 34. Synthesis and antitumor activity of non-polyglutamylatable inhibitors of dihydrofolate reductase.

J. Med. Chem. 34 , 222, (1991)

Five analogues of methotrextate (MTX), 10-deazaaminopterin (10-DAM), and 10-ethyl-10-deazaaminopterin (10-EDAM) in which the glutamate moiety was replaced by either a gamma-methyleneglutamate or beta-hydroxyglutamate were synthesized and evaluated for their a...

Synthesis , 530, (1990)