Choline chloride
Choline chloride structure
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Common Name | Choline chloride | ||
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| CAS Number | 67-48-1 | Molecular Weight | 139.624 | |
| Density | 1.205 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C5H14ClNO | Melting Point | 302-305 °C (dec.)(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Choline partially prevents the impact of ethanol on the lipid raft dependent functions of l1 cell adhesion molecule.
Alcohol. Clin. Exp. Res. 38(11) , 2722-30, (2014) Fetal alcohol spectrum disorder, the leading known cause of mental retardation, is caused by alcohol exposure during pregnancy. One mechanism of ethanol (EtOH) teratogenicity is the disruption of the functions of L1 cell adhesion molecule (L1). These function... |
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Pregnancy and lactation alter biomarkers of biotin metabolism in women consuming a controlled diet.
J. Nutr. 144(12) , 1977-84, (2014) Biotin functions as a cofactor for several carboxylase enzymes with key roles in metabolism. At present, the dietary requirement for biotin is unknown and intake recommendations are provided as Adequate Intakes (AIs). The biotin AI for adults and pregnant wom... |
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Highly efficient extraction of anthocyanins from grape skin using deep eutectic solvents as green and tunable media.
Arch. Pharm. Res. 38 , 2143-52, (2015) Deep eutectic solvents (DESs) were investigated as tunable, environmentally benign, yet superior extraction media to enhance the extraction of anthocyanins from grape skin, which is usually discarded as waste. Ten DESs containing choline chloride as hydrogen ... |
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Enhanced signal intensity in matrix-free laser desorption ionization mass spectrometry by chemical modification of bionanostructures from diatom cell walls.
Rapid Commun. Mass Spectrom. 28(13) , 1521-9, (2014) Laser desorption ionization for mass spectrometric measurements (LDI MS) is supported by nanostructured materials. This technique helps to overcome known limitations of matrix-assisted laser desorption/ionization (MALDI) and especially avoids interfering sign... |
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The free radical scavenger, edaravone, ameliorates delayed neuropsychological sequelae after acute carbon monoxide poisoning in rabbits.
Undersea Hyperb. Med. 40(3) , 223-9, (2013) The mechanism underlying delayed neuropsychological sequelae (DNS) after acute carbon monoxide (CO) poisoning is unclear. There are no effective treatments for DNS. As part of a new generation of antioxidants, edaravone has been reported to improve clinical o... |
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Conformationally sensitive proximity of extracellular loops 2 and 4 of the γ-aminobutyric acid (GABA) transporter GAT-1 inferred from paired cysteine mutagenesis.
J. Biol. Chem. 289(49) , 34258-66, (2014) The sodium- and chloride-coupled GABA transporter GAT-1 is a member of the neurotransmitter:sodium:symporters, which are crucial for synaptic transmission. Structural work on the bacterial homologue LeuT suggests that extracellular loop 4 closes the extracell... |
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In vitro drug release and biological evaluation of biomimetic polymeric micelles self-assembled from amphiphilic deoxycholic acid-phosphorylcholine-chitosan conjugate.
Mater. Sci. Eng. C. Mater. Biol. Appl. 45 , 162-9, (2014) Novel biomimetic amphiphilic chitosan derivative, deoxycholic acid-phosphorylcholine-chitosan conjugate (DCA-PCCs) was synthesized based on the combination of Atherton-Todd reaction for coupling phosphorylcholine (PC) and carbodiimide coupling reaction for li... |
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Metabolomic profiling of serum in the progression of Alzheimer's disease by capillary electrophoresis-mass spectrometry.
Electrophoresis 35(23) , 3321-30, (2014) There is high interest in the discovery of early diagnostic biomarkers of Alzheimer's disease, for which metabolomics exhibits a great potential. In this work, a metabolomic approach based on ultrafiltration and analysis by CE-MS has been used to obtain repre... |
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Enzymatic properties and substrate specificity of a bacterial phosphatidylcholine synthase.
FEBS J. 281(15) , 3523-41, (2014) Phosphatidylcholine (PC) is a rare membrane lipid in bacteria, but is crucial for virulence of the plant pathogen Agrobacterium tumefaciens and various other pathogens. Agrobacterium tumefaciens uses two independent PC biosynthesis pathways. One is dependent ... |
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Anatomical and electrophysiological changes in striatal TH interneurons after loss of the nigrostriatal dopaminergic pathway.
Brain Struct. Funct. 220(1) , 331-49, (2015) Using transgenic mice that express enhanced green fluorescent protein (EGFP) under the control of the tyrosine hydroxylase (TH) promoter, we have previously shown that there are approximately 3,000 striatal EGFP-TH interneurons per hemisphere in mice. Here, w... |