Amiloride HCl dihydrate
Amiloride HCl dihydrate structure
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Common Name | Amiloride HCl dihydrate | ||
|---|---|---|---|---|
| CAS Number | 17440-83-4 | Molecular Weight | 302.118 | |
| Density | N/A | Boiling Point | 628.1ºC at 760 mmHg | |
| Molecular Formula | C6H13Cl2N7O3 | Melting Point | >240℃ | |
| MSDS | N/A | Flash Point | 333.7ºC | |
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Uptake of different crystal structures of TiO₂ nanoparticles by Caco-2 intestinal cells.
Toxicol. Lett. 226(3) , 264-76, (2014) The gastrointestinal uptake of different crystal structures of TiO2 was investigated using Caco-2 intestinal cells. Caco-2 monolayers exhibited time-dependent, saturable uptake of Ti from TiO2 exposures of 1 mgl(-1) over 24h, which was influenced by crystal t... |
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Gemini surfactants mediate efficient mitochondrial gene delivery and expression.
Mol. Pharm. 12(3) , 716-30, (2015) Gene delivery targeting mitochondria has the potential to transform the therapeutic landscape of mitochondrial genetic diseases. Taking advantage of the nonuniversal genetic code used by mitochondria, a plasmid DNA construct able to be specifically expressed ... |
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SLC4A11 is an EIPA-sensitive Na(+) permeable pHi regulator.
Am. J. Physiol. Cell Physiol. 305(7) , C716-27, (2013) Slc4a11, a member of the solute linked cotransporter 4 family that is comprised predominantly of bicarbonate transporters, was described as an electrogenic 2Na(+)-B(OH)4(-) (borate) cotransporter and a Na(+)-2OH(-) cotransporter. The goal of the current study... |
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Mechanosensitive Ca²⁺-permeable channels in human leukemic cells: pharmacological and molecular evidence for TRPV2.
Biochim. Biophys. Acta 1848(1 Pt A) , 51-9, (2015) Mechanosensitive channels are present in almost every living cell, yet the evidence for their functional presence in T lymphocytes is absent. In this study, by means of the patch-clamp technique in attached and inside-out modes, we have characterized cationic... |
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Probing the endocytic pathways of the filamentous bacteriophage in live cells using ratiometric pH fluorescent indicator.
Adv. Healthc. Mater. 4(3) , 413-9, (2015) Viral nanoparticles have attracted extensive research interests in diverse applications of diagnosis and therapy. In particular, filamentous M13 bacteriophages have shown great potential in biomedical applications. However, its pathways entering into cells st... |
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[It is possible to reduce drug-drug interactions. Interactions were corrected frequently by patient-specific letters to general practitioners].
Lakartidningen. 110(48) , 2176-7, (2013)
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Pharmacology and pathophysiology of mutated KCNJ5 found in adrenal aldosterone-producing adenomas.
Endocrinology 155(4) , 1353-62, (2014) Somatic mutations of the potassium channel KCNJ5 are found in 40% of aldosterone producing adenomas (APAs). APA-related mutations of KCNJ5 lead to a pathological Na(+) permeability and a rise in cytosolic Ca(2+), the latter presumably by depolarizing the memb... |
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Inhibition of influenza virus replication by targeting broad host cell pathways.
PLoS ONE 9(10) , e110631, (2014) Antivirals that are currently used to treat influenza virus infections target components of the virus which can mutate rapidly. Consequently, there has been an increase in the number of resistant strains to one or many antivirals in recent years. Here we comp... |
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Epinephrine stimulation of anion secretion in the Calu-3 serous cell model.
Am. J. Physiol. Lung Cell. Mol. Physiol. 306(10) , L937-46, (2014) Calu-3 is a well-differentiated human bronchial cell line with the characteristics of the serous cells of airway submucosal glands. The submucosal glands play a major role in mucociliary clearance because they secrete electrolytes that facilitate airway hydra... |
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Potentiated macrophage activation by acid sensing under low adiponectin levels.
Mol. Immunol. 57(2) , 141-50, (2014) Adiponectin can protect against inflammation; one of the mechanisms involves direct, inhibition of macrophages (MΦ). We postulated that adiponectin anti-sense transgenic (AsTg) mice raised in our laboratory are prone to inflammation because of systemic low ad... |