Luxalbendazole
Luxalbendazole structure
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Common Name | Luxalbendazole | ||
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| CAS Number | 90509-02-7 | Molecular Weight | 365.336 | |
| Density | 1.6±0.1 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C15H12FN3O5S | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | N/A | |
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Activity of luxabendazole against liver flukes, gastrointestinal roundworms, and lungworms in naturally infected sheep.
Parasitol. Res. 75(1) , 14-8, (1988) The anthelmintic potential of luxabendazole was investigated in sheep harboring mixed naturally acquired helminth infections. Results were assessed by comparing worm counts of the treated groups (seven animals each) on days 7-8 posttreatment with those of the... |
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Determination of luxabendazole in biological fluids by high-performance liquid chromatography.
J. Chromatogr. A. 578(2) , 321-6, (1992) Luxabendazole, a new benzimidazole, is a highly potent broad-spectrum anthelmintic. A high-performance liquid chromatographic method has been developed for its determination in serum and urine samples. In order to optimize the clean-up of samples we compared ... |
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Biochemical effects of luxabendazole on Trichinella spiralis.
Parasitol. Res. 76(6) , 518-20, (1990) Biochemical changes produced by luxabendazole in muscle-stage Trichinella spiralis larvae consisted of a decrease in free glucose and glycogen levels (46.71% and 35.66%, respectively) after in vivo treatment, slight in vitro inhibition of fumarate reductase a... |
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Bacterial mutagenic evaluation of Luxabendazole, a new broad spectrum anthelmintic, with the Salmonella typhimurium His- and the Escherichia coli Tryp- reversion tests.
Mutagenesis 11(1) , 27-31, (1996) Luxabendazole is a new benzimidazole carbamate chemotherapeutic agent, which has proved to be effective against adult and immature stages of the major gastrointestinal nematodes, trematodes and cestodes. The mutagenic properties of Luxabendazole were investig... |
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The intestinal absorption of Luxabendazole in rats.
J. Pharm. Biomed. Anal. 12(11) , 1471-4, (1994)
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Effects of luxabendazole on the tegument of Fasciola hepatica.
J. Helminthol. 68(1) , 73-80, (1994) The effects in vivo of 5, 10, and 20 mg/kg of luxabendazole (LBZ) on the tegument of Fasciola hepatica have been examined 48 h, 7 days and 14 days post-treatment of experimentally-infected rats. As early as 48 h post-treatment, the drug is shown to provoke si... |
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Pharmacokinetics of luxabendazole after oral and intravenous administration to sheep.
Am. J. Vet. Res. 58(11) , 1263-6, (1997) To determine pharmacokinetics of luxabendazole after oral and i.v. administration to healthy sheep.7 clinically normal female Merino sheep between 9 and 12 months old.Pharmacokinetics were determined after oral and i.v. administration of luxabendazole at a do... |
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Pharmacokinetics of intravenous luxabendazole in rabbits: influence of the enterohepatic circulation.
Biopharm. Drug Dispos. 19(5) , 341-7, (1998) Luxabendazole (LBZ) is a new benzimidazole carbamate chemotherapeutic agent, which has proved to be very effective against adult and immature stages of the major gastrointestinal nematodes, trematodes and cestodes. While information on the efficacy of LBZ in ... |