2-(N-Morpholino)ethanesulfonic acid monohydrate

2-(N-Morpholino)ethanesulfonic acid monohydrate Structure
2-(N-Morpholino)ethanesulfonic acid monohydrate structure
Common Name 2-(N-Morpholino)ethanesulfonic acid monohydrate
CAS Number 145224-94-8 Molecular Weight 213.252
Density 1.349 g/cm3 Boiling Point N/A
Molecular Formula C6H15NO5S Melting Point >300 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

A-803467, a tetrodotoxin-resistant sodium channel blocker, modulates ABCG2-mediated MDR in vitro and in vivo.

Oncotarget 6 , 39276-91, (2015)

ATP-binding cassette subfamily G member 2 (ABCG2) is a member of the ABC transporter superfamily proteins, which has been implicated in the development of multidrug resistance (MDR) in cancer, apart from its physiological role to remove toxic substances out o...

Motesanib (AMG706), a potent multikinase inhibitor, antagonizes multidrug resistance by inhibiting the efflux activity of the ABCB1.

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Cancer cells often become resistant to chemotherapy through a phenomenon known as multidrug resistance (MDR). Several factors are responsible for the development of MDR, preeminent among them being the accelerated drug efflux mediated by overexpression of ATP...

Design and development of novel mitochondrial targeted nanocarriers, DQAsomes for curcumin inhalation.

Mol. Pharm. 11(7) , 2334-45, (2014)

Curcumin has potent antioxidant and anti-inflammatory properties but poor absorption following oral administration owing to its low aqueous solubility. Development of novel formulations to improve its in vivo efficacy is therefore challenging. In this study, ...

Multivalent linkers for improved covalent binding of oligonucleotides to dye-doped silica nanoparticles.

Nanotechnology 26 , 365703, (2015)

This paper describes the fabrication of oligonucleotide-coated Cy5-doped silica nanoparticles using a combination of multivalent linkers and their use in surface-based DNA sandwich hybridization assays. Dipodal silane is introduced as a means to fabricate ami...

Highly sensitive DNA detection using cascade amplification strategy based on hybridization chain reaction and enzyme-induced metallization.

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A novel highly sensitive colorimetric assay for DNA detection using cascade amplification strategy based on hybridization chain reaction and enzyme-induced metallization was established. The DNA modified superparamagnetic beads were demonstrated to capture an...

Quantitative Characterization of Magnetic Mobility of Nanoparticle in Solution-Based Condition.

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Magnetic nanoparticles are considered as the ideal substrate to selectively isolate target molecules or organisms from sample solutions in a wide variety of applications including bioassays, bioimaging and environmental chemistry. The broad array of these app...

Functional fabrication of recombinant human collagen-phosphorylcholine hydrogels for regenerative medicine applications.

Acta Biomater. 12 , 70-80, (2014)

The implant-host interface is a critical element in guiding tissue or organ regeneration. We previously developed hydrogels comprising interpenetrating networks of recombinant human collagen type III and 2-methacryloyloxyethyl phosphorylcholine (RHCIII-MPC) a...

Cellphone-based detection platform for rbST biomarker analysis in milk extracts using a microsphere fluorescence immunoassay.

Anal. Bioanal. Chem 406(27) , 6857-66, (2014)

Current contaminant and residue monitoring throughout the food chain is based on sampling, transport, administration, and analysis in specialized control laboratories. This is a highly inefficient and costly process since typically more than 99% of the sample...

Identification of the Same Na(+)-Specific DNAzyme Motif from Two In Vitro Selections Under Different Conditions.

J. Mol. Evol. 81 , 225-34, (2015)

We report an investigation of the functional relationship between two independently selected RNA-cleaving DNAzymes, NaA43, and Ce13, through in vitro selection. The NaA43 DNAzyme was obtained through a combination of gel-based and column-based in vitro select...

Hydrophilic, bactericidal nanoheater-enabled reverse osmosis membranes to improve fouling resistance.

ACS Appl. Mater. Interfaces 7 , 11117-26, (2015)

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