5-propyl-2-thiouracil

5-propyl-2-thiouracil Structure
5-propyl-2-thiouracil structure
Common Name 5-propyl-2-thiouracil
CAS Number 2954-52-1 Molecular Weight 170.23200
Density 1.24g/cm3 Boiling Point N/A
Molecular Formula C7H10N2OS Melting Point N/A
MSDS Chinese USA Flash Point N/A
Symbol GHS08
GHS08
Signal Word Warning

Proper migration and axon outgrowth of zebrafish cranial motoneuron subpopulations require the cell adhesion molecule MDGA2A.

Biol. Open 4(2) , 146-54, (2015)

The formation of functional neuronal circuits relies on accurate migration and proper axonal outgrowth of neuronal precursors. On the route to their targets migrating cells and growing axons depend on both, directional information from neurotropic cues and ad...

Tweedle cuticular protein BmCPT1 is involved in innate immunity by participating in recognition of Escherichia coli.

Insect Biochem. Mol. Biol. 58 , 76-88, (2015)

Bombyx mori, a lepidopteran insect, is one of the earliest models for pattern recognition of Gram-negative bacteria, which may induce the IMD pathway for production of antibacterial peptides. So far, several recognition proteins have been reported in B. mori....

Transferrin and thyroid hormone converge in the control of myelinogenesis.

Exp. Neurol. 265 , 129-41, (2015)

Myelination is a concerted mechanism tightly regulated in the brain. Although several factors are known to participate during this process, the complete sequence of events is far from being fully elucidated. Separate effects of apotransferrin (aTf) and thyroi...

Cellular Anti-Melanogenic Effects of a Euryale ferox Seed Extract Ethyl Acetate Fraction via the Lysosomal Degradation Machinery.

Int. J. Mol. Sci. 16 , 9217-35, (2015)

The aim of this study was to investigate the effect of ethyl acetate fraction of Euryale ferox seed extracts (Efse-EA) on melanogenesis in immortalized mouse melanocyte cell line, melan-a. Efse-EA showed strong dose-dependent mushroom tyrosinase inhibitory ac...

Zebrafish as a model for apolipoprotein biology: comprehensive expression analysis and a role for ApoA-IV in regulating food intake.

Dis. Model Mech. 8(3) , 295-309, (2015)

Improved understanding of lipoproteins, particles that transport lipids throughout the circulation, is vital to developing new treatments for the dyslipidemias associated with metabolic syndrome. Apolipoproteins are a key component of lipoproteins. Apolipopro...

The Nimrod transmembrane receptor Eater is required for hemocyte attachment to the sessile compartment in Drosophila melanogaster.

Biol. Open 4(3) , 355-63, (2015)

Eater is an EGF-like repeat transmembrane receptor of the Nimrod family and is expressed in Drosophila hemocytes. Eater was initially identified for its role in phagocytosis of both Gram-positive and Gram-negative bacteria. We have deleted eater and show that...

Towards autotrophic tissue engineering: Photosynthetic gene therapy for regeneration.

Biomaterials 75 , 25-36, (2015)

The use of artificial tissues in regenerative medicine is limited due to hypoxia. As a strategy to overcome this drawback, we have shown that photosynthetic biomaterials can produce and provide oxygen independently of blood perfusion by generating chimeric an...

Nr2f1b control venous specification and angiogenic patterning during zebrafish vascular development.

J. Biomed. Sci. 22 , 104, (2015)

The specification of vein and the patterning of intersegmental vessels (ISV) controlled by transcription factor is not fully characterized. The orphan nuclear receptor Chicken ovalbumin upstream promoter transcription factor II (CoupTFII, a.k.a NR2F2) positiv...

A Caged Ret Kinase Inhibitor and its Effect on Motoneuron Development in Zebrafish Embryos.

Sci. Rep. 5 , 13109, (2015)

Proto-oncogene tyrosine-protein kinase receptor RET is implicated in the development and maintenance of neurons of the central and peripheral nervous systems. Attaching activity-compromising photocleavable groups (caging) to inhibitors could allow for externa...

Testosterone and estradiol treatments differently affect pituitary-thyroid axis and liver deiodinase 1 activity in orchidectomized middle-aged rats.

Exp. Gerontol. 72 , 85-98, (2015)

We previously reported that orchidectomy (Orx) of middle-aged rats (15-16-month-old; MA) slightly affected pituitary-thyroid axis, but decreased liver deiodinase (Dio) type 1 and pituitary Dio2 enzyme activities. At present, we examined the effects of subsequ...