O-Tritylhydroxylamine

O-Tritylhydroxylamine Structure
O-Tritylhydroxylamine structure
Common Name O-Tritylhydroxylamine
CAS Number 31938-11-1 Molecular Weight 275.344
Density 1.1±0.1 g/cm3 Boiling Point 443.2±44.0 °C at 760 mmHg
Molecular Formula C19H17NO Melting Point 79-81ºC(lit.)
MSDS Chinese USA Flash Point 235.1±22.1 °C
Symbol GHS07
GHS07
Signal Word Warning

Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.

Bioorg. Med. Chem. 18 , 2225-31, (2010)

There are many of pathogen parasite species with different susceptibility profile to antiparasitic drugs. Unfortunately, almost QSAR models predict the biological activity of drugs against only one parasite species. Consequently, predicting the probability wi...

Antimalarial and antileishmanial activities of histone deacetylase inhibitors with triazole-linked cap group.

Bioorg. Med. Chem. 18(1) , 415-25, (2010)

Histone deacetylase inhibitors (HDACi) are endowed with plethora of biological functions including anti-proliferative, anti-inflammatory, anti-parasitic, and cognition-enhancing activities. Parsing the structure-activity relationship (SAR) for each disease co...

Design and synthesis of novel histone deacetylase inhibitor derived from nuclear localization signal peptide

Bioorg. Med. Chem. Lett. 19(23) , 6588-90, (2009)

We describe herein the synthesis and characterization of a new class of histone deacetylase (HDAC) inhibitors derived from conjugation of a suberoylanilide hydroxamic acid-like aliphatic-hydroxamate pharmacophore to a nuclear localization signal peptide. We f...