5-TAMRA-SE
5-TAMRA-SE structure
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Common Name | 5-TAMRA-SE | ||
|---|---|---|---|---|
| CAS Number | 150810-68-7 | Molecular Weight | 527.525 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C29H25N3O7 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
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Biothiol-triggered, self-disassembled silica nanobeads for intracellular drug delivery.
Acta Biomater. 23 , 263-70, (2015) Silica-based nanomaterials have demonstrated great potential in biomedical applications due to their chemical inertness. However, the degradability and endosomal trapping issues remain as rate-limiting barriers during their innovation. In this study, we provi... |
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Fusion of a short peptide that binds immunoglobulin G to a recombinant protein substantially increases its plasma half-life in mice.
PLoS ONE 9(7) , e102566, (2014) We explore a strategy to substantially increase the half-life of recombinant proteins by genetic fusion to FcIII, a 13-mer IgG-Fc domain binding peptide (IgGBP) originally identified by DeLano and co-workers at Genentech [DeLano WL, et al. (2000) Science 287:... |
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Cholesterol-Enriched Domain Formation Induced by Viral-Encoded, Membrane-Active Amphipathic Peptide.
Biophys. J. 110 , 176-87, (2016) The α-helical (AH) domain of the hepatitis C virus nonstructural protein NS5A, anchored at the cytoplasmic leaflet of the endoplasmic reticulum, plays a role in viral replication. However, the peptides derived from this domain also exhibit remarkably broad-sp... |
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Chemical methods of DNA and RNA fluorescent labeling.
Nucleic Acids Res. 24 , 4535, (1996) Several procedures have been described for fluorescent labeling of DNA and RNA. They are based on the introduction of aldehyde groups by partial depurination of DNA or oxidation of the 3'-terminal ribonucleoside in RNA by sodium periodate. Fluorescent labels ... |
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A subnanomolar fluorescent probe for protein kinase CK2 interaction studies.
Org. Biomol. Chem. 10 , 8645-8653, (2012) Up-regulation of an acidophilic protein kinase, CK2, has been established in several types of cancer. This cognition has made CK2 an important target for drug development for cancer chemotherapy. The characterization of potential drug candidates, determinatio... |
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High-affinity bisubstrate probe for fluorescence anisotropy binding/displacement assays with protein kinases PKA and ROCK.
Anal. Biochem. 385 , 85-93, (2009) The bisubstrate fluorescent probe ARC-583 (Adc-Ahx-(D-Arg)(6)-d-Lys(5-TAMRA)-NH2) and its application for the characterization of both ATP- and protein/peptide substrate-competitive inhibitors of protein kinases PKA (cyclic AMP-dependent protein kinase) and R... |
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Fluorescence quenching by TEMPO: a sub-30 A single-molecule ruler.
Biophys. J. 89 , L37-39, (2005) A series of DNA molecules labeled with 5-carboxytetramethylrhodamine (5-TAMRA) and the small nitroxide radical TEMPO were synthesized and tested to investigate whether the intramolecular quenching efficiency can be used to measure short intramolecular distanc... |
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An investigation on interaction between 14mer DNA oligonucleotide and CTAB by fluorescence and fluorescence resonance energy transfer studies.
J. Phys. Chem. B 114 , 7602-7608, (2010) Possible interaction mechanisms between oligonucleotide (DNA) of 14 base pairs with cetyl trimethyl ammonium bromide (CTAB) were postulated based on fluorescence and fluorescence resonance energy transfer (FRET) studies. Detailed FRET investigations were carr... |
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Fluorometric TLC assay for evaluation of protein kinase inhibitors.
Anal. Biochem. 340 , 165-170, (2005) A fluorometric assay for measuring protein kinase activity has been developed. The assay is based on the separation of fluorescently marked substrate 5-carboxytetramethylrhodamine-kemptide (5-TAMRA-kemptide) from its phosphorylated counterpart by TLC and quan... |