Trimethyl-Gallium

Trimethyl-Gallium Structure
Trimethyl-Gallium structure
Common Name Trimethyl-Gallium
CAS Number 1445-79-0 Molecular Weight 114.82700
Density 1,151 g/cm3 Boiling Point 55.7ºC
Molecular Formula C3H9Ga Melting Point -15.8ºC
MSDS Chinese USA Flash Point -18°C
Symbol GHS02 GHS05
GHS02, GHS05
Signal Word Danger

Novel Dammarane-Type Triterpene Saponins from Panax ginseng Root.

Chem. Pharm. Bull. 63 , 927-34, (2015)

Four phytochemical constituents were isolated from Panax ginseng root by repeated column chromatography (CC), medium pressure liquid chromatography (MPLC), high-speed counter current chromatography (HSCCC), and semi-preparative HPLC. Their structures were elu...

Structure-activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors.

Bioorg. Med. Chem. 23(9) , 2024-34, (2015)

Recently we described a novel pyranopyridine inhibitor (MBX2319) of RND-type efflux pumps of the Enterobacteriaceae. MBX2319 (3,3-dimethyl-5-cyano-8-morpholino-6-(phenethylthio)-3,4-dihydro-1H-pyrano[3,4-c]pyridine) is structurally distinct from other known G...

Measuring decreased serum IgG sialylation: a novel clinical biomarker of lupus.

Lupus 24 , 948-54, (2015)

The aim of this work was to develop a simple assay to distinguish between patients with rheumatoid arthritis (RA) and patients with systemic lupus erythematosus (SLE) by measuring the serum sialylated IgG (SAIgG).Using a newly established SNA-based ELISA meth...

Exometabolom analysis of breast cancer cell lines: Metabolic signature.

Sci. Rep. 5 , 13374, (2015)

Cancer cells show characteristic effects on cellular turnover and DNA/RNA modifications leading to elevated levels of excreted modified nucleosides. We investigated the molecular signature of different subtypes of breast cancer cell lines and the breast epith...

Refined candidate region for F4ab/ac enterotoxigenic Escherichia coli susceptibility situated proximal to MUC13 in pigs.

PLoS ONE 9(8) , e105013, (2014)

F4 enterotoxigenic Escherichia coli (F4 ETEC) are an important cause of diarrhea in neonatal and newly-weaned pigs. Based on the predicted differential O-glycosylation patterns of the 2 MUC13 variants (MUC13A and MUC13B) in F4ac ETEC susceptible and F4ac ETEC...

CO2 capture systems based on saccharides and organic superbases.

Faraday Discuss. 183 , 429-44, (2015)

In this report, novel systems, based on highly abundant saccharides, D-mannose, D-glucose, β-cyclodextrin, alginic acid and mannitol, in combination with an organic superbase, tetramethylguanidine (TMG) or 1,8-diazabicyclo[5.4.0]undec-7-ene (DBU), are studied...

Alteration of O-GlcNAcylation affects serine phosphorylation and regulates gene expression and activity of pyruvate kinase M2 in colorectal cancer cells.

Oncol. Rep. 34 , 1933-42, (2015)

O-GlcNAcylation is a dynamic post-translational modification that has extensive crosstalk with phosphorylation either at the same or adjacent sites of various proteins. We have previously reported that O-GlcNAcylation level was increased in primary breast and...

U1 snRNP is mislocalized in ALS patient fibroblasts bearing NLS mutations in FUS and is required for motor neuron outgrowth in zebrafish.

Nucleic Acids Res. 43 , 3208-18, (2015)

Mutations in FUS cause amyotrophic lateral sclerosis (ALS), but the molecular pathways leading to neurodegeneration remain obscure. We previously found that U1 snRNP is the most abundant FUS interactor. Here, we report that components of the U1 snRNP core par...

Lung CD8+ T Cell Impairment Occurs during Human Metapneumovirus Infection despite Virus-Like Particle Induction of Functional CD8+ T Cells.

J. Virol. 89 , 8713-26, (2015)

Human metapneumovirus (HMPV) is a major cause of respiratory disease in infants, the elderly, and immunocompromised individuals worldwide. There is currently no licensed HMPV vaccine. Virus-like particles (VLPs) are an attractive vaccine candidate because the...

Endothelial progenitor cells as a possible component of stem cell niche to promote self-renewal of mesenchymal stem cells.

Mol. Cell Biochem. 397(1-2) , 235-43, (2014)

Stem cells dwell at the "stem cell niche" to accomplish a series of biological processes. The composition of the niche should be determined because the insufficient understanding of this feature limits the development in the study of stem cells. We showed in ...