4H-pyrido[3,2-b][1,4]oxazin-3-one

4H-pyrido[3,2-b][1,4]oxazin-3-one Structure
4H-pyrido[3,2-b][1,4]oxazin-3-one structure
Common Name 4H-pyrido[3,2-b][1,4]oxazin-3-one
CAS Number 20348-09-8 Molecular Weight 150.13500
Density 1.328g/cm3 Boiling Point 384.159ºC at 760 mmHg
Molecular Formula C7H6N2O2 Melting Point 204-206 °C(lit.)
MSDS Chinese USA Flash Point N/A
Symbol GHS07
GHS07
Signal Word Warning

Synthesis and biological evaluation of oxadiazole derivatives as inhibitors of soluble guanylyl cyclase.

Bioorg. Med. Chem. 18(3) , 1288-96, (2010)

Soluble guanylyl cyclase (sGC) is an ubiquitously expressed enzyme that generates the second messenger cGMP and hence, leads to a number of physiological responses including vasodilation, inhibition of platelet aggregation and neurotransmission. Whilst many a...