Nitroglycerin
Nitroglycerin structure
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Common Name | Nitroglycerin | ||
|---|---|---|---|---|
| CAS Number | 55-63-0 | Molecular Weight | 227.08600 | |
| Density | 1.671 g/cm3 | Boiling Point | 295.8ºC at 760 mmHg | |
| Molecular Formula | C3H5N3O9 | Melting Point | 144 - 146ºC | |
| MSDS | N/A | Flash Point | 12°C | |
| Symbol |
GHS02 |
Signal Word | Danger | |
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Aldehyde dehydrogenase-independent bioactivation of nitroglycerin in porcine and bovine blood vessels.
Biochem. Pharmacol. 93(4) , 440-8, (2015) The vascular bioactivation of the antianginal drug nitroglycerin (GTN), yielding 1,2-glycerol dinitrate and nitric oxide or a related activator of soluble guanylate cyclase, is catalyzed by aldehyde dehydrogenase-2 (ALDH2) in rodent and human blood vessels. T... |
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Society of cardiovascular anesthesiologists: the effect of blood pressure regulation during aortic coarctation repair on brain, kidney, and muscle oxygen saturation measured by near-infrared spectroscopy: a randomized, clinical trial.
Anesth. Analg. 116(4) , 760-6, (2013) In this study, we compared the effects of 3 frequently used arterial blood pressure-regulating agents on brain (rScO2), renal (SrO2), and muscle (SmO2) oxygen saturation, during aortic coarctation repair in children. Based on the reported adverse effect of so... |
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Transdermal nitroglycerin for the treatment of preterm labor: a systematic review and metaanalysis.
Am. J. Obstet. Gynecol. 209(6) , 551.e1-551.e18, (2013) The purpose of this study was to evaluate the efficacy and safety of transdermal nitroglycerin as a tocolytic agent in women with preterm labor.We conducted a systematic review and metaanalysis of randomized controlled trials.Thirteen studies were included (1... |
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Severe pre-eclampsia and hypertensive crises.
Best Pract. Res. Clin. Obstet. Gynaecol. 27(6) , 877-84, (2013) Hypertensive disorders of pregnancy are one of the leading causes of peripartum morbidity and mortality globally. Hypertensive disease in pregnancy is associated with a spectrum of severity, ranging from mild pregnancy-induced hypertension to eclampsia. Altho... |
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Prognostic significance of atrial fibrillation and severity of symptoms of heart failure in patients with low gradient aortic stenosis and preserved left ventricular ejection fraction.
Am. J. Cardiol. 114(11) , 1722-8, (2014) The aims of this study were to investigate the clinical outcomes of patients with low-gradient aortic stenosis despite preserved left ventricular ejection fraction and to assess reliable prognostic clinical-instrumental features in patients experiencing or no... |
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Topical glyceryl trinitrate ointment for pain related to anal hypertonia after stapled hemorrhoidopexy: a randomized controlled trial.
Dis. Colon Rectum 56(6) , 768-73, (2013) Postoperative pain after stapled hemorrhoidopexy is cause for considerable concern and may be related to contracture of continence muscles.We compared glyceryl trinitrate 0.4% ointment with lidocaine chlorohydrate 2.5% gel as topical therapy to relieve the pa... |
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48-year-old man with cough and leg swelling.
Mayo Clin. Proc. 87(12) , e105-8, (2012)
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St. John's wort relieves pain in an animal model of migraine.
Eur. J. Pain 17(3) , 369-81, (2013) Despite the substantial improvement that antimigraine drugs brought to migraineurs, there is the need for a long-acting and better tolerated migraine treatment than actual pharmacotherapy. St. John's wort (SJW), a medicinal plant endowed with a favourable tol... |
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Topical diltiazem vs. topical glyceril trinitrate in the treatment of chronic anal fissure: a prospective, randomized, double-blind trial.
Acta Gastroenterol. Belg. 75(4) , 438-42, (2012) Chemical sphincterotomy is a new way for the treatment of chronic anal fissure which avoids the risk of faecal incontinence associated with traditional surgical methods. The aim of this study was to compare topical Diltiazem with topical Glyceril trinitrate i... |
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Efficacy of nitric oxide, with or without continuing antihypertensive treatment, for management of high blood pressure in acute stroke (ENOS): a partial-factorial randomised controlled trial.
Lancet 385(9968) , 617-28, (2015) High blood pressure is associated with poor outcome after stroke. Whether blood pressure should be lowered early after stroke, and whether to continue or temporarily withdraw existing antihypertensive drugs, is not known. We assessed outcomes after stroke in ... |