4-Fluoro-2-(trifluoromethyl)benzoic acid
4-Fluoro-2-(trifluoromethyl)benzoic acid structure
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Common Name | 4-Fluoro-2-(trifluoromethyl)benzoic acid | ||
|---|---|---|---|---|
| CAS Number | 141179-72-8 | Molecular Weight | 208.110 | |
| Density | 1.5±0.1 g/cm3 | Boiling Point | 239.0±40.0 °C at 760 mmHg | |
| Molecular Formula | C8H4F4O2 | Melting Point | 121-124 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 98.3±27.3 °C | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Quantitative structure-metabolism relationships for substituted benzoic acids in the rat. Computational chemistry, NMR spectroscopy and pattern recognition studies.
Biochem. Pharmacol. 44(10) , 1935-46, (1992) An extensive set of computed molecular properties, both steric and electronic, have been calculated using molecular orbital and empirical methods for benzoic acid (1) and a congeneric series of substituted benzoic acids, i.e. 2-, 3- and 4-fluorobenzoic acids ... |
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Benzazepinone Nav1.7 blockers: potential treatments for neuropathic pain.
Bioorg. Med. Chem. Lett. 17(22) , 6172-7, (2007) A series of benzazepinones were synthesized and evaluated as hNa(v)1.7 sodium channel blockers. Several compounds from this series displayed good oral bioavailability and exposure and were efficacious in a rat model of neuropathic pain. |
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