Labetalol HCl
Labetalol HCl structure
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Common Name | Labetalol HCl | ||
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| CAS Number | 32780-64-6 | Molecular Weight | 364.87 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 552.7±50.0 °C at 760 mmHg | |
| Molecular Formula | C19H25ClN2O3 | Melting Point | 187-189° | |
| MSDS | Chinese USA | Flash Point | 288.1±30.1 °C | |
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Myoglobin microplate assay to evaluate prevention of protein peroxidation.
J. Pharm. Biomed. Anal. 114 , 305-11, (2015) The current therapeutic strategies are based on the design of multifunctional drug candidates able to interact with various disease related targets. Drugs that have the ability to scavenge reactive oxygen species (ROS), beyond their main therapeutic action, m... |
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The alpha- and beta-adrenoceptor blocking activities of labetalol and its RR-SR (50:50) stereoisomers.
Br. J. Pharmacol. 104 , 823-828, (1991) 1. We compared the alpha 1-, alpha 2- and beta 1-adrenoceptor blocking potencies of labetalol with those of its two stereoisomers (RR and SR) in pithed rats and in homogenized rat cerebral cortex and heart. 2. In pithed rats, labetalol and the RR-SR combinati... |
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Acute hypertension promotes hemorrhagic transformation in a rabbit embolic stroke model: effect of labetalol.
Exp. Neurol. 150 , 153, (1998) We examined the relationship between acute hypertension following cerebral embolization and subsequent hemorrhagic transformation (HT) in a rabbit embolic stroke model. We have shown previously that the likelihood and severity of hemorrhage were significantly... |
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Effects of two antihypertensive agents, labetalol and metoprolol, on the production of reactive oxygen species by normal polymorphonuclear leukocytes in vitro.
Hypertens. Pregnancy 18 , 239-247, (1999) Increased lipid peroxidation is a putative causal factor for preeclampsia. Because oxygen free radicals are involved in inducing the lipid oxidation chain reaction, we evaluated two beta adrenoreceptor blockers, labetalol and metoprolol, currently used for tr... |