Betaxolol hydrochloride
Betaxolol hydrochloride structure
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Common Name | Betaxolol hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 63659-19-8 | Molecular Weight | 343.889 | |
| Density | N/A | Boiling Point | 448ºC at 760 mmHg | |
| Molecular Formula | C18H30ClNO3 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 224.7ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Development and validation of stability-indicating TLC-densitometric method for determination of betaxolol with LC-ESI/MS analysis of degradation product.
Acta Pol. Pharm. 70(4) , 643-52, (2013) The purpose of this work was to develop a sensitive stability indicating TLC-densitometric method for the determination of betaxolol (Bx) in pharmaceutical preparations and to study the stability of Bx in acidic solutions. The method was developed on TLC alum... |
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Comparison of the Progression Rates of the Superior, Inferior, and Both Hemifield Defects in Normal-Tension Glaucoma Patients
Am. J. Ophthalmol. 154(6) , 958-968.e1, (2012) Purpose To investigate the progression rates of superior and inferior hemifield defects and each hemifield in bihemifield defects in normal-tension glaucoma patients and to compare the progression rates of each hemifield between groups in eyes with similar ba... |
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Microcalorimetric and spectrographic studies on the interaction of DNA with betaxolol.
Int. J. Pharm. 386(1-2) , 165-71, (2010) The interaction of calf thymus deoxyribonucleic acid (ct-DNA) with betaxolol (BET) in aqueous buffer solution (pH 7.40) has been investigated using isothermal titration calorimetry (ITC), ultraviolet absorption (UV), fluorescence spectroscopy (FS) and circula... |
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Persistence of glaucoma medical therapy in the Glasgow Glaucoma Database.
Br. J. Ophthalmol. 95(7) , 966-70, (2011) To report the persistence of glaucoma medical therapy in a database of 1006 patients with ocular hypertension (OHT), normal tension glaucoma (NTG) and primary open-angle glaucoma (POAG) attending the Glaucoma Clinic at Glasgow Royal Infirmary, Glasgow, UK.Ana... |
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The structure of betaxolol studied by infrared spectroscopy and natural bond orbital theory.
Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 76(3-4) , 395-400, (2010) Betaxolol is a selective beta(1) receptor blocker used in the treatment of hypertension and glaucoma. A study of the betaxolol structure based on infrared spectroscopy and natural bond orbital (NBO) theory is the main aim of the present research. FTIR spectra... |
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Betaxolol hydrochloride ophthalmic suspension 0.25% and timolol gel-forming solution 0.25% and 0.5% in pediatric glaucoma: a randomized clinical trial.
J. AAPOS 13(4) , 384-90, (2009) To describe the safety profile and clinical response on elevated intraocular pressure (IOP) of betaxolol hydrochloride ophthalmic suspension 0.25% (betaxolol) and timolol maleate ophthalmic gel-forming solution (TGFS) (0.25% and 0.5%), in subjects under 6 yea... |
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Application of kinetic resolution using HCS as chiral auxiliary: novel synthesis of beta-blockers (S)-betaxolol and (S)-metoprolol.
Chirality 21(8) , 745-50, (2009) Optically pure (S)-betaxolol and (S)-metoprolol were prepared with an extremely facile and practical method using kinetic resolution of beta-amino alcohols employing HCS as chiral auxiliary. High enantiomeric purity (ee > 99%) was achieved and the synthetic s... |
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Direct intra-accumbal infusion of a beta-adrenergic receptor antagonist abolishes WIN 55,212-2-induced aversion.
Neurosci. Lett. 500(1) , 82-5, (2011) The cannabinoid system is known to interact with a variety of neuromodulators in the central nervous system and impacts diverse behaviors. Previous studies have demonstrated that limbic norepinephrine is a critical determinant in the behavioral expression of ... |
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Allergic contact dermatitis due to carteolol, with good tolerance to betaxolol.
Dermatitis 22(4) , 232-3, (2011)
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Allergic contact dermatitis due to the beta-blocker betaxolol in eyedrops, with cross-sensitivity to timolol.
Contact Dermatitis 62(5) , 319-20, (2010)
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