L-NIL dihydrochloride
L-NIL dihydrochloride structure
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Common Name | L-NIL dihydrochloride | ||
|---|---|---|---|---|
| CAS Number | 159190-45-1 | Molecular Weight | 260.161 | |
| Density | N/A | Boiling Point | 369ºC at 760 mmHg | |
| Molecular Formula | C8H19Cl2N3O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 177ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Effects of nitric oxide synthase deficiency on a disintegrin and metalloproteinase domain-containing protein 12 expression in mouse brain samples.
Mol. Med. Report. 12 , 2253-62, (2015) A disintegrin and metalloproteinase domain-containing protein 12 (ADAM12) belongs to the ADAM family of transmembrane proteins. Via proteolysis, cell adhesion, cell-cell fusion, cell-matrix interaction and membrane protein shedding, ADAM proteins are involved... |
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Leptin administration activates irisin-induced myogenesis via nitric oxide-dependent mechanisms, but reduces its effect on subcutaneous fat browning in mice.
Int. J. Obes. 39(3) , 397-407, (2015) BACKGROUND/OBJETIVES: Obese leptin-deficient ob/ob mice exhibit high adiposity and reduced muscle mass with leptin replacement promoting weight loss and inducing muscle accretion through PGC-1α-dependent mechanisms. Our aim was to analyze in vivo and in vitro... |
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L-N6-(1-iminoethyl)lysine: a selective inhibitor of inducible nitric oxide synthase.
J. Med. Chem. 37 , 3886, (1994) L-N6-(1-Iminoethyl)lysine (L-NIL) has been synthesized and is shown to be both a potent and selective inhibitor of mouse inducible nitric oxide synthase (miNOS). L-NIL has an IC50 of 3.3 microM for miNOS compared to an IC50 of 92 microM for rat brain constitu... |