Acetylcholine Bromide
Acetylcholine Bromide structure
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Common Name | Acetylcholine Bromide | ||
|---|---|---|---|---|
| CAS Number | 66-23-9 | Molecular Weight | 226.111 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C7H16BrNO2 | Melting Point | 140-143 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Frequency-dependent, cell type-divergent signaling in the hippocamposeptal projection.
J. Neurosci. 34(35) , 11769-80, (2014) Hippocampal oscillations are critical for information processing, and are strongly influenced by inputs from the medial septum. Hippocamposeptal neurons provide direct inhibitory feedback from the hippocampus onto septal cells, and are therefore likely to als... |
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S-equol Partially Restored Endothelial Nitric Oxide Production in Isoflavone-deficient Ovariectomized Rats.
J. Cardiovasc. Pharmacol. 65 , 500-7, (2015) S-equol is known as an estrogenic substance, but its ability to restore vascular endothelial function is unknown. The aim of this study was to investigate the impact of S-equol on endothelial function and intimal thickening under isoflavone- and estrogen-defi... |
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Vasorelaxant activities of Danhong injection and their differential effects on the rat abdominal aorta and mesenteric artery.
J. Cardiovasc. Pharmacol. 65(1) , 62-71, (2015) Previous studies have found that Danhong injection (DHI), an extensively used herbal extract preparation in China, might be a powerful vasodilator. The aims of this study were to determine the vascular activity of DHI and its effects on arteries of different ... |
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Gulf War agent exposure causes impairment of long-term memory formation and neuropathological changes in a mouse model of Gulf War Illness.
PLoS ONE 10(3) , e0119579, (2015) Gulf War Illness (GWI) is a chronic multisymptom illness with a central nervous system component such as memory deficits, neurological, and musculoskeletal problems. There are ample data that demonstrate that exposure to Gulf War (GW) agents, such as pyridost... |
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The PI3K-Akt-eNOS pathway is involved in aortic hyporeactivity to Phenylephrine associated with late pregnancy in spontaneously hypertensive rats.
Life Sci. 122 , 78-86, (2015) This study aimed to evaluate the effects of Wortmannin, an inhibitor of phosphatidylinositol 3-kinase (PI3K)/protein kinase B (Akt), on aortic hyporeactivity to Phenylephrine (Phe) and nitric oxide bioavailability associated with pregnancy in hypertensive rat... |
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Muscarinic receptors modulate dendrodendritic inhibitory synapses to sculpt glomerular output.
J. Neurosci. 35(14) , 5680-92, (2015) Cholinergic [acetylcholine (ACh)] axons from the basal forebrain innervate olfactory bulb glomeruli, the initial site of synaptic integration in the olfactory system. Both nicotinic acetylcholine receptors (nAChRs) and muscarinic acetylcholine receptors (mACh... |
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Benzofuran-chalcone hybrids as potential multifunctional agents against Alzheimer's disease: synthesis and in vivo studies with transgenic Caenorhabditis elegans.
ChemMedChem 9(12) , 2671-84, (2014) In the search for effective multifunctional agents for the treatment of Alzheimer's disease (AD), a series of novel hybrids incorporating benzofuran and chalcone fragments were designed and synthesized. These hybrids were screened by using a transgenic Caenor... |
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Curcumin analogues inhibit phosphodiesterase-5 and dilate rat pulmonary arteries.
J. Pharm. Pharmacol. 67(1) , 87-95, (2014) Phosphodiesterase (PDE)-5 inhibitors are useful as vasodilators for the treatment of pulmonary arterial hypertension. We aimed to study curcumin analogues for PDE5 inhibitory activity and vasorelaxation of rat pulmonary arteries.Three natural curcuminoids (1-... |
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Phosphatidylinositol4-phosphate 5-kinase prevents the decrease in the HERG potassium current induced by Gq protein-coupled receptor stimulation.
J. Pharmacol. Sci. 127(1) , 127-34, (2015) The human ether-a-go-go-related gene (HERG) potassium current (IHERG) has been shown to decrease in amplitude following stimulation with Gq protein-coupled receptors (GqRs), such as α1-adrenergic and M1-muscarinic receptors (α1R and M1R, respectively), at lea... |
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RAGE mediates the inactivation of nAChRs in sympathetic neurons under high glucose conditions.
Eur. J. Neurosci. 41(3) , 341-51, (2015) Autonomic dysfunction is a serious complication of diabetes and can lead to cardiovascular abnormalities and premature death. It was recently proposed that autonomic dysfunction is triggered by oxidation-mediated inactivation of neuronal nicotinic acetylcholi... |