(1R)-(-)-(1-AMINOPROPYL)PHOSPHONICACID
(1R)-(-)-(1-AMINOPROPYL)PHOSPHONICACID structure
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Common Name | (1R)-(-)-(1-AMINOPROPYL)PHOSPHONICACID | ||
|---|---|---|---|---|
| CAS Number | 66254-56-6 | Molecular Weight | 153.11700 | |
| Density | 1.295g/cm3 | Boiling Point | 302.9ºC at 760 mmHg | |
| Molecular Formula | C4H12NO3P | Melting Point | 272-277ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | 137ºC | |
| Symbol |
GHS07 |
Signal Word | Warning | |
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Peptide synthesis catalyzed by an antibody containing a binding site for variable amino acids.
Science 265 , 234, (1994) Monoclonal antibodies, induced with a phosphonate diester hapten, catalyzed the coupling of p-nitrophenyl esters of N-acetyl valine, leucine, and phenylalanine with tryptophan amide to form the corresponding dipeptides. All possible stereoisomeric combination... |
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Synthesis and structure-activity relationships of antibacterial phosphonopeptides incorporating (1-aminoethyl)phosphonic acid and (aminomethyl)phosphonic acid.
J. Med. Chem. 29 , 29, (1986) Phosphonodipeptides and phosphonooligopeptides based on L- and D-(1-aminoethyl)phosphonic acids L-Ala(P) and D-Ala(P) and (aminomethyl)phosphonic acid Gly(P) at the acid terminus have been synthesized and investigated as antibacterial agents, which owe their ... |
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New alpha-amino phosphonic acid derivatives of vinblastine: chemistry and antitumor activity.
J. Med. Chem. 34 , 1998, (1991) A series of new amino phosphonic acid derivatives of vinblastine (1, VLB) has been synthesized and tested in vitro and in vivo for antitumor activity. The compounds were obtained from O4-deacetyl-VLB azide. All of the new products studied were capable of inhi... |
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Renin inhibitors. Synthesis of transition-state analogue inhibitors containing phosphorus acid derivatives at the scissile bond.
J. Med. Chem. 32 , 1652, (1989) The synthesis of five amino phosphorus derivatives, 1a-e, is described. The derivatives were incorporated into a series (18) of analogues of the 5-14 portion of angiotensinogen, in most cases at the scissile Leu-Val bond. The resultant compounds were tested i... |
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Synthesis of novel N-phosphonoalkyl dipeptide inhibitors of human collagenase.
J. Med. Chem. 37 , 158, (1994) The synthesis of a series of N-phosphonalkyl dipeptides 6 is described. Syntheses were devised that allowed the preparation of single diastereoisomers and the assignment of stereochemistry. The compounds were evaluated in vitro for their ability to inhibit th... |
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Camp, N.P. et al.
Bioorg. Med. Chem. Lett. 2 , 1047, (1992)
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